Thermo Fisher Scientific Unveils a New Solution to Increase Sensitivity of In Vitro Toxicity Testing

The Thermo Scientific Cellomics ToxInsight IVT Platform

Boston, MA., (June 9, 2009) – Thermo Fisher Scientific Inc., the world leader in serving science, today announced the launch of the Thermo Scientific Cellomics ToxInsight Solution at the World Pharmaceutical Congress, June 9-11 2009, Philadelphia. The Thermo

Scientific Cellomics ToxInsight Solution offers a unique combination of imaging hardware and analysis software, and couples pre-validated panels of toxicity assessment targets, to provide a robust risk assessment tool for in vitro toxicity testing.

Traditional methods of assessing toxicity in vitro measure single targets and have a record of low predictive power. Recent published research has shown that cellular imaging, which combines multiple toxicity targets in single cells provides better indicators of compound toxicity. Such rich profiles of cellular toxicity have the potential to revolutionize the way toxicity testing is performed, from reducing late stage drug failures due to adverse toxicity (hence lowering overall drug development costs), to better understanding of the effect of environmental toxins as well as ensuring the products we use from shampoos to topical skin treatments are safe.

Harnessing the power of cell imaging to make multiple toxicity assessments on a cell by cell basis, the ToxInsight IVT Platform, for the first time, unites automated instrumentation, software, and reagent ‘cartridges’ within a simple, intuitive workflow, offering improved sensitivity and specificity compared to traditional methods. ToxInsight delivers the tools needed to drive a new standard for in vitro toxicity testing, allowing deeper insights and better decisions to be made earlier in the discovery process.

The ToxInsight IVT Platform, including the reader hardware, software, and biological assessment cartridges, such as “organelle health” and “proliferation/cell death”, can be seen at the Thermo Scientific booth #203 at the World Pharmaceutical Congress, June 9-11 2009, Philadelphia.

For more information on the Thermo Scientific Cellomics range of products please call 1-800-432-4091. Alternatively please visit www.thermo.com/toxinsight.

Thermo Scientific is part of Thermo Fisher Scientific, the world leader in serving science.

About Thermo Fisher Scientific

Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, enabling our customers to make the world healthier, cleaner and safer. With 2008 revenues of $10.5 billion, we have approximately 34,000 employees and serve over 350,000 customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as environmental and industrial process control settings. Serving customers through two premier brands, Thermo Scientific and Fisher Scientific, we help solve analytical challenges from routine testing to complex research and discovery. The Thermo Scientific brand represents a complete range of high-end analytical instruments as well as laboratory equipment, software, services, consumables and reagents to enable integrated laboratory workflow solutions. Fisher Scientific provides a complete portfolio of laboratory equipment, chemicals, supplies and services used in healthcare, scientific research, safety and education. Together, we offer the most convenient purchasing options to customers and continuously advance our technologies to accelerate the pace of scientific discovery, enhance value for customers and fuel growth for shareholders and employees alike. Visit www.thermofisher.com

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