WEST CHESTER, Pa. — Chiral Technologies introduces two new immobilized zwitterionic chiral stationary phases, CHIRALPAK ZWIX(+) and CHIRALPAK ZWIX(-). These chiral phases can be used in high-performance liquid chromatography and

have been developed specifically to exhibit stereoselectivity for zwitterionic molecules, notably for separations of underivatized amino acids and peptides.

Methods can be developed on these high-resolution 3-µm supports for analytical and MS- compatible enantiomer separations. The zwitterionic supports are not restricted by the position of the amino and acidic groups in the analyte, and accordingly can be used for the effective separation of alpha, beta and gamma amino acids. In addition, the ZWIX phases can be used for the separation of any amphoteric compound.

The zwitterionic ion exchangers, combining anion- and cation-exchange functional groups, have been developed by Professor Wolfgang Lindner at the University of Vienna and complement the previously commercialized CHIRALPAK QD-AX and QN-AX anion exchange columns. This technology is globally marketed exclusively by Chiral Technologies.

About Chiral Technologies Worldwide

Chiral Technologies Worldwide, the global leader in enantioselective chromatography, serves pharmaceutical and other life science industries and offers the largest portfolio of chiral stationary phases (CSPs) and analytical and preparative chiral columns for the separation of racemic mixtures into single enantiomers. The company also provides analytical method development and custom separation services. Chiral Technologies Worldwide serves the North and Latin American markets through Chiral Technologies Inc. (West Chester, Pa.), the European market through Chiral Technologies Europe SAS (Illkirch, France), and the Asian market through Daicel Chiral Technologies India and Daicel Chiral Technologies China, all wholly owned subsidiaries of Daicel Corporation. Learn more at www.chiraltech.com, www.chiral.fr, and www.daicelchiraltech.cn.