Polar Bear Plus Flow™ is a compact, state of the art temperature control module for both heated and cooled

flow-through chemistry applications. The unit utilises proprietary heating/cooling technology to

deliver temperatures from 150oC down to -40oC and was developed by Cambridge Reactor Design in conjunction with

Professor Steven Ley’s Research Group in the Innovative Technologies Centre (ITC) at the University of Cambridge,

UK.

Compact & portable: With a footprint not much bigger than a standard hotplate stirrer, unlike conventional -40oC circulators, the Polar Bear Plus Flow™ can be easily relocated in and out of the fume cupboard.

Wide temperature range & rapid equilibration: Advanced cooling technology delivers any set point temperature between -40oC and 150oC, the lowest temperatures being accessible within approximately 30 minutes. Stable temperatures are maintained even with a throughput of 10 ml/min. Reactors: The coil reactor module uses standard Uniqsis reactors and can accommodate single coil reactors up to 60 ml in volume, multiple smaller coils (available in a variety of sizes), and glass static

mixer chips to offer maximum flexibility for the flow chemist.

Reagent Pre-tempering: Reagent solutions can be efficiently tempered to the desired temperature prior to mixing by using either a static mixer chip located in the top of the reactor block, or a series of ‘stacked’ multiple 2.0 ml coils.

Powerful: In tests, the Polar Bear Plus Flow™ was easily able to maintain -40oC conditions even with a flow-through of 10 ml/min (Rt = 5 minutes).

No ‘Icing-up’: A vacuum-jacketed glass cover can be fitted with a nitrogen purge to prevent ice formation under sub-ambient conditions and ensures that the reactor remains clearly visible at all times.

For maximum flexibility the Polar Bear Plus Flow can be controlled in a number of different ways:

Standalone control: the embedded control interface is easy to use and quickly allows a setpoint to be entered and

heating or cooling to be initiated. The Polar Bear Plus Flow automatically equilibrates to the set temperature.

In addition, it is possible to automatically log performance data and to transfer this information to your PC either via USB

or Ethernet.

Control via FlowSyn Interface: the unit can be connected to either a Uniqsis FlowSyn, or a Uniqsis BPM (Binary Pump Module).

On startup, the presence of the Polar Bear Plus is auto-detected and direct control is possible through the FlowSyn or BPM user interface.

Moreover, by integrating with a fraction collector (FlowSyn Multi-X™ Package), a series of experiments, each at a

different temperature from -40oC to +150oC, can be programmed and then automatically performed in sequence. No need to periodically top-up with cardice or use other refridgerants.