Gothenburg, Sweden – 04-05. 2009.

Denator announced today that one of the leading proteomic groups in Europe; the Proteome Research Centre, at UCD Conway Institute, Dublin, Ireland will become a reference centre for the company’s Stabilizor™ T1 system for stabilizing tissue sample from the moment of sampling.

As a reference centre, the Proteome Research Centre at UCD Conway Institute will demonstrate the Stabilizor technology to other potential customers and gain early access to new products for stabilization of biological samples.

Prof. Michael Dunn at the Proteome Research Centre, explained, ‘Degradation begins seconds after sampling, thereby distorting the composition of the in vivo proteome. Denator’s rapid heat inactivation technology ensures complete elimination of enzymatic activity, thereby preserving the intact proteome. This will be an important tool that will help to further our understanding of the molecular basis of biological processes in health and disease.’

Prof. Giuliano Elia, Director of the Proteomics/MS Resource Core Facility added, ‘To gain early access to new products for stabilization of biological samples is naturally of great interest for us and will favor us in our work with different types of samples and applications.’

Olof Sköld, CEO at Denator, concluded: ‘We are very pleased that UCD Conway has decided to implement Stabilizor T1 in their eminent research activities, but above all we’re excited that UCD Conway will become reference centre for the Stabilizor system. Degradation of proteins and peptides during sample preparation is a major bottleneck in proteomic research today, which we also discuss in our latest article Heat Stabilization of the Tissue Proteome: A New Technology for Improved Proteomics (Svensson, et al., J. Proteome Res., 2009, 8 (2), pp 974–981). This will generate an even wider acceptance for our heat inactivation technology from the proteomic research community. We look forward to continuing our collaboration with UCD Conway in the future.’

About Denator

Denator intends to become the leading supplier of products that stabilize biological tissues and fluids at the moment of sampling. Stabilization and standardization of sampling processes upstream significantly enhances the quality of data obtained from analytical techniques used downstream. In proteomic and peptidomic investigations, enhanced data quality increases the reliability of data interpretation and can reveal novel proteins and peptides that would be lost or undetectable when using conventional preparation techniques. Based upon the company’s proprietary heat-inactivation technology platform, Denator is developing solutions that enable scientists to stop sample degradation instantly and maintain the stability of sample components throughout the analytical workflow. Established in 2004, Denator is headquartered at the Biotech Center in Gothenburg, Sweden. For more information visit: www.denator.com or contact: