INDIANAPOLIS -– DuraClone IM premixed dry reagent cocktails from Beckman Coulter Life Sciences standardize and streamline workflow for high content flow cytometry in translational research studies involving identification of cellular sub-populations of the human immune system. Based on collaborative work with the ONE Study consortium, these optimized, easy-to-use panels provide worry-free compensation to minimize labor and reduce variability and errors when characterizing alterations of immune status through detection of human blood-cell subpopulations.

Dried down using a proprietary process that ensures high structural stability, DuraClone IM panels are stable for up to one year at room temperature. Simple, single-step resuspension of DuraClone cocktails by the addition of a cell suspension or whole blood minimizes variability, allowing generation of comparable data, across geographies and institutions.

“Collaborating with Beckman Coulter scientists has furthered our ability to conduct clinical research studies in the field of organ transplantation, which in the case of the ONE Study will permit us to more accurately assess the effects of various different cell therapies as potential advanced therapeutic products,” said Prof. Edward Geissler, founder of the ONE Study and Head of Experimental Surgery at the University Hospital in Regensburg, Germany.

Professor Birgit Sawitzki, from the Charité Hospital, Institut für Medizinische Immunologie Transplantationstoleranz in Berlin and the leader of the immune monitoring work package of the ONE Study concurred: “Reliable, reproducible results across participating sites are a necessity in multi-institution clinical research studies aiming to characterize changes in immune cell composition.”

DuraClone IM panels comprising basic phenotype, B cells, T-cell subsets and dendritic cells are offered for ‘Research Use Only’ in 25-test packages containing three complete compensation kits with a single-color set of compensation reagents specific for each panel. The kits improve results and simplify workflows across organizations involved in clinical research studies of the human immune system. More information about the panels is available at www.DuraClone.com.

About Beckman Coulter Life Sciences

Beckman Coulter Life Sciences is dedicated to improving the health of people around the world. The company’s global leadership and world-class service and support delivers sophisticated instrument systems, reagents and services to life science researchers in academic and commercial laboratories, enabling new discoveries in biology-based research and development. A leader in centrifugation and flow cytometry, Beckman Coulter has long been an innovator in life sciences instruments and solutions used at the forefront of important areas of investigation, including genomics and proteomics. For more information, please visit www.beckmancoulter.com.

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