SOUTH EASTON, Mass., Dec. 11 — Pressure BioSciences, Inc. (Nasdaq: PBIO – News; “PBI” or the “Company”) and Omni International (“Omni”) today announced that they have entered into a strategic marketing, distribution, and technology co-development Agreement. Under the terms of the Agreement, the companies will: (1) share market data, customer leads, technology assessments, and competitive information; (2) co-promote certain products at industry trade shows beginning in 2009; (3) license Omni to sell PBI’s recently released, patent-pending PCT Shredder to laboratories worldwide; and (4) co-develop new instrumentation and consumables that combine the homogenization capabilities of Omni with the extraction capabilities of PBI, in an effort to provide research scientists with a targeted approach to better solve certain sample preparation issues.

Mr. Karl Jahn, President of Omni, said: “PBI is the leading company in the world in providing laboratory scale, ultra-high pressure cycling instrumentation for biomolecule extraction. Omni has been one of the world’s leading suppliers of laboratory scale homogenizers for decades. Our two companies’ technologies are extremely complementary and synergistic. To that end, we believe that combining the advantages of both technologies could offer the customer a range of solutions to ensure efficient extraction for many sample types, particularly those that continue to pose challenges in sample preparation. We are therefore pleased to have PBI, with its wealth of experience, novel technology, and IP, as a strategic business partner, and we look forward to working with them in developing an entirely new concept in solution-based products for the large sample preparation market.”

Mr. Jahn continued: “We also look forward to marketing and selling the PCT Shredder in early 2009. This novel, patent-pending device uses a unique approach to extract high yields of nucleic acids, proteins, lipids, and small molecules from tough, fibrous, and other difficult-to-disrupt samples, such as muscle, skin, plant cell walls, and insects, and with minimal damage to fragile molecules. We believe this product fills an existing customer need, and that utilizing our very effective worldwide distribution network, we can be highly successful in placing this product within our existing customer base. And since the PCT Shredder uses a similar processing container (PULSE Tube©) as used in PBI’s PCT Sample Preparation System, successful placement of the PCT Shredder can lead not only to revenue for both companies, but also to increased visibility of PBI’s PCT Sample Preparation System.”

Mr. Jahn concluded: “PBI has publicly disclosed that they are actively seeking to raise additional capital through equity financing under terms consistent with shareholder approval obtained on September 25, 2008. We will be participating in this financing, as we believe that the technology is sound, the market is large, the future is very bright, and because we want to be an integral part of the new, refocused PBI.

Mr. Richard T. Schumacher, President, and CEO of PBI commented: “Omni has an extensive homogenization product line (including high throughput automated equipment) that has been recognized for years for its quality and dependability. They continually develop new and improved homogenization products to satisfy changing customer needs. They have also been very successful in marketing and distributing their products through effective distribution channels in every major market in the world. We are very pleased to have the opportunity to work with Karl and his team to aggressively distribute the PCT Shredder worldwide, and also to co-develop a new concept in laboratory-scale sample preparation that combines the advantages of both homogenization and PCT extraction.”