Solution Complements Established Small Sample Capabilities to Now Address Virtually All Sample Types

SAN CARLOS, Calif.–NuGEN Technologies, Inc., a leader in nucleic acid amplification and sample preparation, announced today that it has employed its powerful, Single Primer Isothermal Amplification (SPIA®) technology to create a new line of products that offers life scientists a fast, simple, and low-cost solution for routine gene expression analysis. The first members in the Applause™ family include the WT-Amp ST and WT-Amp Plus ST RNA Amplification Systems, designed to prepare cDNA targets from >50 ng total RNA for analysis using Affymetrix GeneChip® Gene ST or Exon ST arrays, respectively.

The addition of Applause brand products expands the NuGEN portfolio which includes the company’s flagship Ovation® family of RNA amplification systems optimized for particularly small (down to a single cell) and degraded specimens. Applause products are specifically designed to address specimens in which RNA is more abundant (>50 ng) and intact, such as fresh-frozen tissue and cultured cells. This addition makes NuGEN’s proprietary SPIA technology available for use with virtually all sample types for downstream microarray- or qPCR-based gene expression analysis, from small and degraded samples to larger and pristine samples.

“The Applause WT-Amp Systems answer the gene expression customer need for fast, simple, low cost sample preparation solutions, while maintaining the superior quality and sensitivity of NuGEN’s proven SPIA technology,” explained Dr. Joe Don Heath, senior director, NuGEN technical marketing. “Researchers have been tremendously successful with NuGEN Ovation products for their most difficult samples and have asked for a cost-effective complement to prepare their ‘everyday’ samples with the same SPIA-caliber quality and sensitivity.”

With the launch of Applause RNA Amplification Systems, NuGEN demonstrates its commitment to developing a family of “green” nucleic acid sample preparation solutions. The Applause box is made from 100% recycled post-consumer waste materials. According to NuGEN chief executive officer, Elizabeth A. Hutt, the company plans to donate a portion of the proceeds to address global environmental concerns. “We believe it is our responsibility to do our part to protect the environment. The life sciences are inextricably linked to the environmental sciences. This is one way NuGEN can help conserve the environment and better the overall human condition.”

Both new Applause systems will be available in 24-reaction packaging. They may be purchased directly from NuGEN or through its global network of distributors.

For more information on NuGEN Applause WT-Amp ST or Applause WT-Amp Plus ST RNA Amplification Systems, contact NuGEN Technologies at 888-654-6544 or email a representative at custserv@nugeninc.com.

About NuGEN

NuGEN Technologies, Inc. (www.nugeninc.com), based in San Carlos, CA, is focused on the development and commercialization of sensitive, rapid, and high-throughput amplification and sample preparation systems to enable the comprehensive analysis and discovery of biological mechanisms, cellular responses, and disease pathologies.

NuGEN, Ovation, SPIA and Ribo-SPIA are registered trademarks of NuGEN Technologies, Inc. WT-Ovation, FL-Ovation, Applause and Imagine More From Less are trademarks or service marks of NuGEN Technologies, Inc. All other marks are the property of their respective owners.

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