Millersburg, PA –– ASI, manufacturer of single-use systems and technologies and Chromatan a single-use chromatography solutions provider, announced today an exclusive agreement between the two companies to combine

development, sales, marketing and manufacturing efforts to bring CCTC – a continuous, single-use and column-free purification technology to market. This agreement leverages the strengths of ASI’s single-use manufacturing, sales and marketing expertise with Chromatan’s innovative scientific and technical development expertise.

“Chromatan has done a fantastic job of creating an innovation that is going to change the course of protein purification in bioprocessing,” said Kent Smeltz, ASI’s President.

Oleg Shinkazh, founder and CEO of Chromatan said: “We are thrilled to partner with ASI, who is a global leader in single-use systems to help us commercialize this exciting new technology”Under the terms of the agreement, ASI and Chromatan will complete the development of the newly patented technology and launch the purification system during the fourth quarter of 2013.

About ASI

ASI is a leading global provider of advanced single-use systems for the Healthcare and Life Sciences Industries. ASI’s fully customized systems and high-quality services offer the flexibility to maximize efficiencies, minimize costs and alleviate risks in the production of bio-pharmaceutical processes and patient-care devices. The company owns and operates development and manufacturing centers in the United States and Mexico. ASI’s Quality Management System and award-winning ERP system gives them the ability to provide an un-paralleled level of customization rapidly and error free. These systems combined with over twenty-five years of experience are the reason ASI can provide systems built to the customers’ process, in the industry’s shortest lead-time, with the highest level of quality

About Chromatan

Chromatan is a company based in State College, PA. The company’s Continuous Countercurrent Tangential Chromatography (CCTC) is a newly patented technology for purification of biologics. In contrast to conventional column chromatography, where the resin particles are packed in a fixed bed column, CCTC utilizes the resin in a slurry form

which flows through a series of static mixers and hollow fiber membrane modules. CCTC is operated as a continuous process, with all of the chromatographic operations such as binding, washing, elution and stripping performed simultaneously. The operation increases throughput 5 to 10-fold when compared to conventional columns enabling high resin cycling in a single batch. CCTC makes single-use capture practical and introduces significant cost savings of up to 65 percent to the end user.