LifeSensors, Inc. manufactures Ubiquitin Proteasome Pathway (UPP) research tools and novel recombinant protein expression technologies

MALVERN, Pa. & SAN DIEGO–Nacalai USA, Inc. has entered into a distribution agreement with LifeSensors, Inc., a Malvern, Pennsylvania, based biotechnology company for distribution of LifeSensors’ Ubiquitin Proteasome Pathway (UPP) research tools and novel recombinant protein expression technologies in Japan, Singapore, South Korea and Taiwan. Domestically, products are available directly from LifeSensors, Inc.

The agreement was executed in August of 2009 and will allow researchers in Japan, South Korea, Taiwan, and Singapore access to the innovative reagents necessary to facilitate and improve their research and drug discovery efforts.

Products

Ubiquitin Research Tools: Novel technologies such as the CHOP reporter and soon to be introduced Ubiquitin Ligase Kits will allow researchers to demonstrate novel isopeptidase activity, determine substrate specificity of a Ub/Ubl isopeptidase, and measure activity of difficult enzymes such as the Cop9 signalosome.

Expression Technologies: LifeSensors has patented the use of SUMO (Small Ubiquitin-like Modifier) as a fusion tag for recombinant protein expression in eukaryotic and prokaryotic systems. Benefits of this system include improved solubility and dramatically increased yield of the protein of interest. In addition, the tag is efficiently and cost effectively removed with no residual residues or “ragged” ends often associated with competing technologies.

About LifeSensors, Inc.

LifeSensors, Inc. is the leading producer of tools that facilitate the study the Ubiquitin Proteasome Pathway (UPP) and also develops novel technologies that use SUMO to overcome bottlenecks in protein production. LifeSensors’ novel technologies enable research once not possible, and its traditional tools (associated enzymes, substrates, inhibitors) are the highest quality available.

About Nacalai USA and Nacalai Tesque

Nacalai USA, Inc. is the wholly-owned subsidiary of Nacalai Tesque, Inc., Kyoto Japan, founded in 2005 in San Diego, California to bridge between the United States and Japan in the scientific research community. Nacalai USA strives to bring the most innovative and stringently quality-controlled biochemicals and research tools from Japan into the United States market, and also to introduce United States technologies and products into the Japanese and other Asian research markets.