PORT WASHINGTON, N.Y. – Pall Life Sciences, a division of global filtration, separation and purification leader Pall Corporation, is pleased to announce the commercial launch of the Cadence BioSMB Process system single-use flow path, continuous multi-column chromatography system. It has been designed for linear scale-up of an existing PD-scale continuous purification process to a GMP-compliant process-scale continuous purification using feedstreams derived from fed batch bioreactors of up to 2,000L volume.

The Cadence BioSMB Process system can operate with up to eight chromatography columns. It features integrated single-use pump heads, a valve cassette, sensors and flow path to support various chromatographic steps, while also reducing cleaning validation needs. Furthermore, the open platform of the system allows for the use of multiple chromatographic technologies. Ultimately, the chromatographic sorbents are used more efficiently, resulting in smaller column volumes and improved process e