Ethica M: NEW High-Throughput Organ-on-a-Chip Solution

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As the global leader in automated patch clamping technology, we proudly announce the launch of Ethica M, our next-generation high throughput organ-on-a-chip contractility solution.

Building on more than 25 years of scientific and engineering excellence in high-throughput electrophysiology, we now enter the emerging field of microphysiological systems with an automated and standardized platform for human-relevant muscle contractility research.

Ethica M empowers researchers to accelerate drug discovery and safety screening with real-time, functional data from 3D engineered human tissues — delivering predictive insights into drug effects, toxicity, and disease modeling while reducing the need for animal testing.

Automation, Scalability, and Human-Relevant Data

“Ethica M is the natural next step for Sophion. We’re bringing the same precision, scalability, and reliability that we pioneered in automated patch clamping into the organ-on-a-chip space. The hardest part of any experiment is where biology meets material — and with decades of experience getting that right, we now bring the same confidence and performance to a new domain, helping researchers move from data to decision, faster and with fewer resources,” says Michel Krall Jürgens, CEO

At the core, Ethica M is an intuitive and automated solution designed for ease of use and scalability. The solution includes a pipetting robot, optical measurement system with integrated pacing, acquisition and analysis software, 96 well plate consumables with integrated electrodes, and ready-to-use cell kits — offering a turnkey solution for both cardiac and skeletal muscle contractility assays.

Enabling Efficient and Ethical Preclinical Innovation

With unmatched throughput, low cell use (less than 50,000 cells per tissue), and compatibility with standard 96-well lab formats, Ethica M simplifies experiment setup and delivers more consistent, human-relevant results.

In alignment with the 3Rs — Replace, Refine, and Reduce — Ethica M supports a more ethical and sustainable approach to preclinical research, without compromising on safety, data quality or decision-making speed.

With the launch of Ethica M we mark a significant expansion in our mission to advance safer, faster, and more human-relevant drug discovery.

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