Madison, WI — BellBrook Labs announced today that their RGScreen™ Assay technology for detecting “regulator of G-protein signaling” (RGS) protein activity, can be used to identify inhibitors of the RGS4 protein, which was identified in a groundbreaking new study as a promising target for Parkinson’s disease. The RGScreen™ platform combines genetically engineered G proteins with […]

LANCASTER, Calif — Simulations Plus, Inc.,a leading provider of consulting services and software for pharmaceutical discovery and development, today announced that preliminary testing shows that one of the molecules it has designed to inhibit the malaria parasite has been shown to be a potent inhibitor of the malaria parasite. Dr. Robert Clark, director of life […]

Bromodomains (BRDs) are 110 amino acid long domains that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine. The ability of bromodomain regulators to alter chromatin status and control gene expression is important in the development of certain human cancers, adipogenesis, energy metabolism and inflammation. Bromodomains are emerging as a […]

ST. LOUIS, — Sigma-Aldrich Corporation recently completed a 57,000-square-foot expansion of its Bangalore, India, campus. The expansion, which includes an expanded distribution center and new packaging facility, enhances the Company’s distribution capabilities in the Asia-Pacific region, increasing operational excellence in one of the industry’s key markets. The new additions complement existing R&D, custom synthesis and […]

Goettingen, Germany,– Thousands of cellular reactions use nucleotides, either alone or in combination with other substrates. Enzymes in the purinome alone – those that use adenine and guanine nucleotides – comprise 13% of the coding capacity of the human genome. Of these, protein kinases have become highly validated drug targets, but lipid kinases, chaperone ATPases […]

PROXY Laboratories B.V. (“PROXY”) announces today the acquisition of MicroSafe Services (Leiden, the Netherlands), from Merck Millipore, the Life Science division of Merck KGaA, Darmstadt, Germany. MicroSafe is a microbiological contract laboratory that delivers a complete range of critical testing and consultancy services for the development and production of (bio)pharmaceuticals. In addition to offering the […]

Somerset, NJ.– LABVANTAGE announced today that its laboratory information management system (LIMS) and electronic laboratory notebook (ELN) were selected by a world-class provider that specializes in in vitro infectious disease diagnostics, including designing, developing, manufacturing and marketing reagents and automated instruments for medical analyses and cosmetics, and product quality control in the agro-food and pharmaceutical […]

Europe’s largest biorepository – Biobank Graz (Graz, Austria) has reported on its use of sample storage consumables and data management software from Micronic Europe to safeguard its blood, serum and plasma samples. Biobank Graz is a non-profit making service facility of the Medical University Graz, which supports the search for the underlying causes of disease […]

Ann Arbor, MI- 3D Biomatrix, a leader in the development of three-dimensional (3D) cell culture products, has collaborated with Eppendorf to produce definition files for automated dispensing of media into 3D Biomatrix’s Perfecta3D[TM] Hanging Drop Plates. For users of the epMotion systems, these protocols will allow for high throughput cell culture automation and spheroid formation […]

MADISON, WIS.,– Cellular Dynamics International, Inc. (CDI), the world’s largest commercial producer of human induced pluripotent stem (iPS) cell lines and tissue cells for drug discovery and safety, today announced several customer presentations of studies employing the company’s iCell® products at the Society of Toxicology (SOT) Annual Meeting on March 11 to 15 in San […]