Certara Acquires Simulation Software Company
Simcyp’s software platform models and simulates PK outcomes and drug-drug interactions in virtual clinical populations based on in vitro data. Such software provides time and cost savings and can allow companies to simulate response among different virtual population types, including different ethnicities. Other products include Simcyp Paediatric Simulator and Simcyp Animal. Consortium members are company customers. Simcyp will collaborate with Certara’s Tripos unit to relate molecular structure to drug disposition and with Certara’s Pharsight business to extend its reach into clinical trial simulation, IVIVC (in vitro/in vivo correlation) and PK/PD modeling and stimulation.
St. Louis, MO 2/24/12; Sheffield, UK 2/24/12; Sheffield, UK 2/24/12—Certara, a provider of drug discovery and development software and scientific consulting services, has acquired Simcyp for $32 million. Based in the UK, Simcyp supplies a modeling and simulation platform for predicting the fate of drugs in virtual populations. For its fiscal year ending July 2011, Simcyp’s post-tax profit was £1.9 million ($3.0 million = £0.64 = $1), according to Fusion IP, which owned a 20% share of Simcyp. “From a translational science perspective, Simcyp’s preclinical simulation technologies, which include prediction of drug-drug interactions, fit perfectly between Certara’s existing discovery and clinical research offerings, thus enabling an end-to-end solution,” stated Certara President and CEO Jim Hopkins. “For example, this means broader capabilities to predict drug disposition as a function of molecular structure, and the ability to utilize a single unified suite of tools to facilitate preclinical and clinical PBPK [physiologically based pharmacokinetic] and PKPD [pharmacokinetic/pharmacodynamic] modeling and analysis.” Operating as a Certara business unit, Simcyp will maintain its Consortium business model and focus on population-based PBPK/PD modeling and simulation services and software for the pharmaceutical industry. The transaction is expected to be completed on February 29.

