Lab reactors are generally used to optimize or reproduce large-scale chemical reactions at the lab bench. While simple, manual units make up the majority of the market, advanced systems equipped with sensors that control temperature, pH and pressure have become a more significant part of the market. Controlled lab reactors (CLR) typically employ a glass or corrosion-resistant metal vessel whose contents are continuously monitored and controlled. Accessories for these devices often provide a wider range of controlled environments. These platforms are generally preconfigured or automated with a broad spectrum of sizes, adjustable ranges and specifications.

Advanced CLRs function as a closed-loop circuit. They utilize a control system with an active feedback loop that maintains set parameters. The manual controls are software based and typically provide feedback of the vessel’s internal environment with an option for controlling it. CLRs have heating systems that provide uniform heat throughout the vessel with an adjustable thermal level. Temperature is modulated by a jacketed mechanism around the vessel, in which thermally controlled fluid is circulated. Other parameters such as pressure and pH are managed through secondary pumps.

Radleys manufactures the Lara system, which is capable of performing jacketed reactions from 100 mL to 10 L. This system is either preconfigured with set maximum temperature and pressure thresholds or fully customizable. Additionally, Radleys offers the option of single- or dual-vessel platforms.

Parr Instrument exclusively produces chemical reactors and associated equipment. Its Series 5500 HP Compact system has vessels with sizes from 25–600 mL, and each reactor can be tailored based on specific maximum working pressure and temperature thresholds of 0–3000 psi and 0°–275° C, respectively. Each vessel utilizes magnetic drives for stirring with a variable speed motor.

Providing models for lab- and industrial-scale environments, IKA offers the LR-2 line of controlled lab reactors, which features automated options and an overhead mixing design. They have a working maximum temperature of 230° C and utilize a vessel size ranging from 500 mL to 2 L.

Advancements in technology are fueling growth for CLRs, particularly for systems that offer increased parameter thresholds and outputs. Initial systems represent a large fraction of the market. However, aftermarket components, add-ons and accessories are experiencing robust growth as users make adjustments and upgrade their systems.

CLRs are important to organic chemical and petroleum labs, particularly for process development applications. CLRs are also used in the pharmaceutical industry and academia. The market for CLR systems was estimated at less than $10 million in 2013 and represents a small portion of the total lab reactor market.

Controlled Lab Reactors at a Glance:

Leading Suppliers

• Radleys

• IKA

• Parr Instrument

Largest Markets

• Organic Chemicals

• Petroleum

• Pharmaceutical

Instrument Cost

• $5,000–$15,000