Company Announcements

In July, Pall, a Danaher company, extended its consumables distribution agreement with KANEKA to include the next generation KANEKA KanCapA 3G sorbent for the primary capture of monoclonal antibodies from clarified cell culture. Pall currently distributes KANEKA’s KanCapA Protein A chromatography sorbents.

Metrohm announced in July that its ICs can now be controlled by Waters’ Empower CDS. Empower Software has over 475,000 users worldwide.

In August, MilliporeSigma announced that it will open in the first quarter of 2019 its first Mobius Single­-use Manufacturing Facility in China, located in Wuxi.

In September, BIA Separations opened of a new upstream processing laboratory to support integrated optimization of upstream and downstream process development.

Purolite Life Sciences officially opened in September a 25,833 ft² (2,400 m²) agarose resin manufacturing facility in South Wales, capable of producing 100,000 L annually.

In October, PharmaFluidics entered into a partnership agreement under which it will offer Thermo Fisher Scientific’s custom-made EASY-Spray transfer lines, in combo sets with its μPAC chromatography micro-Chips, to constitute an ultra-high-resolution front-end source platform for Thermo Fisher MS instruments.

In October, the Carlyle Group and GIC announced that Nouryon is the new name of the former AkzoNobel Specialty Chemicals business that it acquired earlier this year (see IBO 4/30/18).

Product Introductions

In July, Phenomenex, a Danaher company, introduced Luna Omega SUGAR, a new Luna Omega phase for sugar analysis by HILIC. The phase is specifically engineered for carbohydrate separation and analysis from food, beverage and pharmaceutical matrices, such as milk, animal feed, wine, soda, fruit and tablets.

DataApex released in July Clarity Chromatography Software 8.0, featuring a graphically enhanced user interface and an expanded portfolio of controlled instruments.

In August, Teledyne ISCO, a Teledyne Technologies company, introduced the CombiFlash NextGen flash chromatography system, consisting of three models: the CombiFlash NextGen 100, which is a basic system; the CombiFlash NextGen 300, which is customizable; and the CombiFlash NextGen 300+, with RFID technology. Depending on the model, the systems support flow rates from 1 to 300 mL/min and operation pressures up to 300 psi.

Agilent Technologies released in August a new version of its CDS, the OpenLab CDS ChemStation Edition, enabling labs to export files in the Allotrope Data Format (ADF), which is designed to standardize the collection, exchange and storage of analytical data. The Allotrope Foundation announced that this is the first release of commercial software that supports the ADF.

In September, Showa Denko launched the Shodex IC SI‒36 4D column, which analyzes anions and is compatible with hydroxide eluents. The combination of the new column and hydroxide eluent does not require two different eluents (gradient system), and can perform separation with a single eluent (isocratic system) within 30 minutes.

3M introduced in September the 3M Emphaze AEX Hybrid Purifier, featuring 2 new laboratory capsules and 1 scale-up capsule that allows evaluations at lab and scale-up volumes. The new Emphaze capsules are sterilization/sanitization compatible and can be used across various aqueous-based biopharmaceutical processes, including vaccine purification.

YMC America released in September the YMC-Triart Bio C4, developed specifically for HPLC and UHPLC separations of intact antibodies and other large proteins. The hybrid silica–based butyl phase is ideal for high-sensitivity analysis using MS friendly mobile phases. It features a 300 Å pore size and is available in 1.9 μm, 3 μm and 5 μm particle sizes.

In October, YMC launched the YMC-SEC MAB column, featuring 3 µm silica base particles with a pore size of 250Å.

In September, Genovis introduced the FabRICATOR-HPLC column for automated antibody analysis. The FabRICATOR HPLC column is an enzyme reactor that allows the transfer of existing methods using the company’s enzymes onto fully automated instruments.

In September, JASCO released new LC and SFC control drivers for SCIEX’s SCIEX Analyst MS software.

In October, Biotage debuted the compact Biotage Selekt flash purification system, and Biotage Sfär family of flash purification columns with various media and sizes ranging from 5 g to 350 g. The new columns can be opened and used in conjunction with Biotage Samplet cartridges.

Trace Elemental Instruments introduced in October the XPREP C-IC, calling it the world’s first automated combustion–IC sample preparation system. The system samples the combustion gas as well as automatically transfers the condensed samples to the IC.

In October, Bio-Works released WorkBeads affimAb, an optimized alkaline-stable resin designed for purification of monoclonal- and polyclonal antibodies in laboratory to process scale.