Proteomics
Two separate research groups have completed MS-based maps of human-protein expression, cataloging nearly all the proteins expressed in the human body. Each paper was published in Nature. Combined, the two groups reported more than 70 million mass spectra. Each study documented more than 17,000 proteins encoded by distinct genes. The Human Proteome Map created by Kim et al. is based on an analysis of 30 different human tissues. Wilhelm et al.’s ProteomicsDB project combines new human-tissue studies with public data to create a database based on 60 human tissues. The number of proteins in the ProteomicsDB project totaled 18,097. The studies join other protein surveys, including the Human Protein Atlas, which used antibody staining, and the Human Proteome Project, which used MS and antibody technology.
Source: Nature Biotechnology