Magnetic particle imaging (MPI) is a relatively new technique that is just now entering commercialization. This in vivo imaging technology offers many unique features that distinguish it from other clinical and research imaging modes, such as MRI and CT. Although there are some commonalities with MRI, MPI is a very distinct imaging mode from MRI. […]
There are plenty of options for compact flow cytometers. The hardware has shrunk to a point where some of these instruments can be held in one hand, making them extremely portable and less expensive than traditional flow cytometers. While these smaller cytometers may not have all the bells and whistles offered by a traditional instrument, […]
The industrial process for converting a liquid solution or slurry into a dry powder is known as spray drying. A typical spray dryer operates by dispersing liquid feed in the form of a mist into a cylindrical chamber, where a stream of hot gas can dry the droplets in a split second. Although the vast […]
Dissolution testing is a method of analyzing the physical properties of solid drugs. An imperative step in drug development and QC, it is required to understand the physical changes in any pharmaceutical ingredient. The tests are performed on all solid and semisolid forms of drugs, such as capsules, tablets, ointments and creams. Hygroscopicity, dissolution and […]
Transmission Electron Microscopy (TEM) is the most powerful electron microscopy method. TEM uses electrons for magnification as opposed to optical microscopy, which utilizes visible light. In TEM, an electron beam is amplified and focused using electromagnetic coils while being fired through the specimen. A final set of lenses then magnifies the electron beam before it […]
One of the more interesting developments in molecular spectroscopy over the past 10 years has been the introduction of spectrometers designed for use with small samples, generally on the order of a microliter. The need for such devices stems primarily from life science researchers. Foremost among the applications that have been enabled by these instruments […]
Moisture analyzers measure the moisture content of solids and liquids, as well as gases. These analyzers can measure trace and abundant amounts of moisture in wet or dry samples. There are a number of different technologies that these systems employ to obtain accurate moisture measurements. Loss-On-Drying (LOD) is a well-known and commonly used moisture analysis […]
While many elements can be quantified by general purpose atomic spectroscopy instruments, there are a number of applications that have created niches for specific techniques dedicated to particular elements of interest. One important species of elemental analyzers is carbon/sulfur analyzers. Carbon and sulfur can be critical elements to measure in a variety of matrices. A […]
After the primary analysis of NGS data, the power of genomic analysis software lies within its ability to perform secondary and tertiary analysis. During secondary analysis, data reads are reassembled and filtered to represent the underlying biology, while tertiary analysis software analyzes variants and their similarities to references. With advancements in technology and the necessity […]
While SEMs are the workhorse method for using electron optics to image samples, there are other alternatives as well that offer their own advantages. Among these are electron probe microanalysis (EPMA), which may also be referred to as “microprobe” for short. EPMA is a surface analysis technique that probes the sample surface with a beam […]
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IBO (Instrument Business Outlook) is a twice-monthly newsletter aimed at providing decision-makers with the latest and most complete information available on the life science and analytical instrument industry, and lab product markets. IBO delivers the latest curated industry news, information and trends, as well as SDi data and analysis to deliver the maximum in industry insight with a minimum time investment for executives and investors.

