Biomolecule separation is generally required in workflows in agricultural, biotechnology, environmental, food and pharmaceutical applications. The type of separation used is crucial for successful product recovery or purification, and reliable delivery of protein composition is important in downstream processing. Bioprocess chromatography is frequently used for downstream processing of cells, including the purification of peptides, oligonucleotides, […]
Hydride generators are accessories used with atomic spectrometers for more sensitive analysis of certain elements. Particular techniques that benefit from hydride generation include atomic absorbance, atomic fluorescence (AFS), ICP and ICP-MS spectroscopy. Generators are specific to each analysis technique, but the underlying processes and results are similar. Yields improve for elements that form hydride compounds, […]
MS systems quantify and identify the chemical composition of a sample by generating its mass spectrum. A mass spectrum is a graph of the relative abundance of detected ions by mass within a sample. The process of generating mass spectra begins with the ionization of the sample, which can be achieved by a variety of […]
Surface area analyzers determine the characteristics of a solid, including how it burns, corrodes or reacts with other materials. Analysis is based on the interaction of the atoms on the surface of the solid material. As these atoms are not completely bound on all sides by other atoms in the solid, they are more reactive […]
By using electrons instead of light to investigate surfaces, SEMs routinely provide imagery at a resolution that exceeds the capabilities of optical microscopes by a couple orders of magnitude. The basic method of SEM involves an electron optics column directing an accelerated beam of electrons at the sample. The interaction of the sample with the […]
Evaporation can be a key part of experimental and production processes. At the production level, it can extend the shelf life of products such as foods and pharmaceuticals. In the laboratory, evaporation can remove solvents from completed chemical syntheses or obtain analytes from wet samples. Evaporation occurs when the molecules at the surface of a […]
An electronic nose (e-nose) is an intelligent sensing device that identifies and classifies the odor profile of vapors. Consisting of a sample-delivery unit, an array of gas sensors and a pattern recognition system, the instrument is designed to not only mimic but also improve upon the human olfactory sense, with its increased sensitivity and lack […]
Over the last few years, understanding of genetic engineering methods has progressed to a new level. The latest method involves clustered regularly interspaced short palindromic repeats (CRISPR). These segments of DNA are characterized by short bacterial virus or plasmid sequences that are interspersed between a series of spacers made up of repeated bases. The function […]
Dynamic mechanical analysis (DMA) is a technique in materials characterization that measures the response of a material to a mechanical force. An applied mechanical force provides a stress on the material, and the material’s resulting reaction, or strain, can be quantified. A simple example is the compressive strain equivalent to the relative change in length […]
A single quadrupole MS (SQMS) system is a mass analyzer with one mass-filtering cluster. SQMS, particularly when paired with UHPLC, is a technique that is becoming more prevalent in routine food analyses, including the detection of polycyclic aromatic hydrocarbons, pesticides and aflatoxins. Traditional methods of food analysis have typically used higher-performing instruments, such as LC/MS/MS […]
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IBO (Instrument Business Outlook) is a twice-monthly newsletter aimed at providing decision-makers with the latest and most complete information available on the life science and analytical instrument industry, and lab product markets. IBO delivers the latest curated industry news, information and trends, as well as SDi data and analysis to deliver the maximum in industry insight with a minimum time investment for executives and investors.

