Postnova Analytics announces the AF2000 MALS – a new temperature controlled Flow Field-Flow Fractionation – MALS system developed to provided unmatched separation, characterization and fractionation of biopharmaceutical proteins.

The AF2000 MALS employs a similar setup to a traditional GPC-MALS system but avoids the limitations of column-based chromatographic separations. In the AF2000 MALS system the liquid chromatography column is replaced by a proprietary separation channel technology that retains molecules based only on size and by the influence of a cross flow as a separation force. Because of the unique design of the system and the absence of any stationary phase, separation on the AF2000 MALS is achieved without exerting shear forces and stress on the proteins and aggregates being separated.

Incorporating Multi-Angle Light Scattering (MALS) and Asymmetric Flow Field-Flow Fractionation (AF4) the AF2000 MALS offers separation over a very broad molar mass and particle size range. With the additional benefit of being able to undertake precisely temperature controlled experiments – the AF2000 MALS is able to achieve separations with higher resolution, reproducibility and recovery then has previously been possible.

For further information please visit www.postnova.com/af2000-overview.html or contact Postnova Analytics on +44-1885-475007 / info.uk@postnova.com.

Founded in 1997, Postnova Analytics is the inventor and leading international supplier of Field-Flow Fractionation (FFF) systems for markets including biopharmaceuticals, polymers, materials, nanotechnology and environmental sciences. Leveraging its unique and patented modular FFF – Light Scattering Platform, Postnova has been able to provide high performance solutions to a wide range of applications. Today the company’s growing product portfolio includes Flow FFF, Centrifugal FFF, Thermal FFF, Size Exclusion Chromatography (SEC), MALS and DLS Light Scattering.  Postnova (www.postnova.com) is located and headquartered in Landsberg am Lech (Germany) and has subsidiaries in the USA, UK and Finland. These offices, in conjunction with a highly qualified and trained distribution network, provide informed local support to customers worldwide.