We are pleased to announce Schrödinger software release 2016-4, which is available for download now. The 2016-4 release is the official release of the completely redesigned Maestro 11 as well as the completely revamped Phase for pharmacophore modeling. We have prepared a full collection of training material to help jumpstart your learning curve with the new Maestro 11 interface through our Training portal. The Maestro 11 interface is the culmination of years of feedback from our users and expert user experience (UX) design, and we are confident that you will enjoy the new modern interface that is designed to save you time in executing common tasks. Click here to learn more about Maestro 11, and to view the list of major new features in 2016-4.