Nottingham, UK: New products for smarter, more representative inhaled product testing will be on display at the Copley Scientific stand at Drug Delivery to the Lungs 24 (DDL 24, 11-13 December 2013, Edinburgh International Conference Centre, Scotland). The latest additions to the Copley Scientific range help to make inhaled testing more efficient and improve the in-vivo relevance of in-vitro test methods. Centre stage will be the new Child Alberta Idealised Throat which is used to gather test data that is of direct relevance to paediatric patients.

All orally inhaled products (OIPs) are characterised in terms of aerodynamic particle size distribution to infer information about where in the lung they may deposit. The highly successful Alberta Idealised Throat (AIT) was developed as an alternative to the standard USP induction port which is used to interface the product with the test equipment during this measurement process. With a standardised, highly reproducible, human like geometry, the AIT has been shown to more accurately simulate the deposition of OIPs in the upper respiratory tract, relative to the USP induction port, making testing more representative of in-vivo behaviour. The new Child Alberta Throat is based on child and infant throat geometry, and extends this facility for more representative testing to those developing products for paediatric patient groups.

Also on display will be the new TPK-R™ critical flow controller, the BAC 2000, breath actuation controller and a new breathing simulator model, the BRS 1100. A reverse version of the TPK™ critical flow controller the TPK-R™ has recently been launched to improve the ergonomics of test set-up for dry powder inhaler (DPI) testing. The BAC 2000 allows for the testing of breath actuated MDIs and together with the BRS 1100, simplify nebuliser testing in accordance with the latest regulatory guidance. In combination, they also provide an efficient solution for characterising MDIs with spacers and valved holding chambers, in line with the strategy outlined in a recently published USP stimuli to the revision process.

To see any of the new equipment or for expert input on any aspect of inhaled product testing, visit the Copley Scientific stand.

www.copleyscientific.com

About Copley Scientific

Copley Scientific is recognised as the world’s leading manufacturer and supplier of inhaler test equipment and is a major provider of testing systems for other pharmaceutical dosage forms. The company is also active in detergent testing, air sampling and aerosol characterisation.

Copley Scientific’s pharmaceutical product range includes test equipment for: delivered dose uniformity and aerodynamic particle size measurement of metered-dose inhalers, dry powder inhalers, nebulizers and nasal sprays; as well as tablets (dissolution, disintegration, friability and hardness) capsules, powders, suppositories and transdermals.

Copley Scientific has offices in the UK and Switzerland. The company works in partnership with aerosol particle science experts MSP Corporation in North America, and also distributes MSP Corporation’s air sampling and aerosol characterisation products throughout Europe.

Serving the pharmaceutical and associated industries, Copley Scientific offers an extensive range of equipment for research, development and quality control, as well as full validation and aftersales services. This broad range of products is supplied and supported worldwide through a network of specialist distributors. www.copleyscientific.com

For further information

Press information

Gill Lancaster, Kapler Communications

Phoenix House, Phoenix Park, Eaton Socon, Cambridgeshire, PE19 8EP, UK

T: +44 (0)1480 471059 F: +44 (0)1480 471069 gill.lancaster@kapleronline.com

Company contact:

Mark Copley, Sales Director, Copley Scientific Limited

Colwick Quays Business Park, Private Road No. 2, Colwick, Nottingham

UK NG4 2JY

Tel: +44 (0)115 961 6229 Fax: +44 (0)115 961 7637

m.copley@copleyscientific.co.uk www.copleyscientific.com

North American Distribution

MSP Corporation

5910 Rice Creek Parkway, Suite 300, Shoreview, MN 55126 USA

Tel: +1 651-287-8100 Fax: +1 651-287-8140

Email: sales@mspcorp.com www.mspcorp.com