AMSBIO has expanded its range of cfPure™ Cell Free DNA Purification Kits for rapid and efficient isolation of circulating cell free DNA (cfDNA).  A new cfPure™Max kit is now available for use on samples of 5mLs volume or greater.

AMSBIO cfPure® kits use silica-coated paramagnetic particles to purify cell free DNA from less than 1 mL to greater than 10 mL of serum or plasma. The buffers were developed to ensure efficient recovery of 100 bp – 500 bp DNA fragments in order to maximize recovery of cell free DNA. The recovered DNA is suitable for a wide range of down-stream applications, such as bisulfite sequencing, NGS, and qPCR.

The cfPure® protocol is rapid and easy, allowing users to process several samples in an hour or less and making it ideal for biomarker screening. Using proprietary silica-coated magnetic bead technology, cfPure® kits are able to efficiently recover low molecular weight cell free DNA during isolation – a key success factor for successful analysis of cfDNA. Designed for scalability, cfPure® kits enable you to use just the number of beads and amount of reagent that you need for your cfDNA extraction.  This also means that the number of extractions per kit is dependent on the amount of sample you wish to purify DNA from.

In addition to being easy to perform, scalable and easy to automate, cfPure® kits allow you to use less magnetic bead solution if you are purifying small amounts of plasma – saving you money. Since cfDNA is typically found at very low concentrations and in a fragmented state, very efficient DNA capture, as provided by AMSBIO’s cfPure™ Cell Free DNA Purification Kits, is vital to provide sensitive and reliable results.

For further information please visit http://www.amsbio.com/circulating-cell-free-DNA.aspx or contact AMSBIO on +44-1235-828200 / +1-617-945-5033 / email [email protected].

Founded in 1987, AMS Biotechnology (AMSBIO) is recognized today as a leading transatlantic company contributing to the acceleration of discovery through the provision of cutting-edge life science technology, products and services for research and development in the medical, nutrition, cosmetics and energy industries. AMSBIO has in-depth expertise in extracellular matrices to provide elegant solutions for studying cell motility, migration, invasion and proliferation. This expertise in cell culture and the ECM allows AMSBIO to partner with clients in tailoring cell systems to enhance organoid and spheroid screening outcomes using a variety of 3D culture systems, including organ-on-a-chip microfluidics.

For drug discovery research, AMSBIO offers assays, recombinant proteins and cell lines. Drawing upon a huge and comprehensive biorepository, AMSBIO is widely recognised as a leading provider of high-quality tissue specimens (including custom procurement) from both human and animal tissues. The company provides unique clinical grade products for stem cell and cell therapy applications these include high quality solutions for viral delivery (lentivirus, adenovirus and adeno-associated virus) in addition to GMP cryopreservation technology.