• Single analyte biomarker kit reagents introduced for the quantification of five human inflammatory cytokines
• First kits available in expanding offering to support biomarker studies

Uppsala, Sweden: Gyros Protein Technologies AB, a leading provider of peptide synthesizers and reagents and a pioneer in automated nanoliter-scale immunoassays, today introduced Gyrolab^® Human Cytokine Kit Reagents, the first in a range of new biomarker kits. These include five single analyte biomarker kit reagents for the quantification of human inflammatory cytokines: human TNF-a, IFN-gamma, IL-6, IL-10 and IL-4. The new Gyrolab^® Human Cytokine Kit Reagents are optimized for use on all Gyrolab systems, offer improved assay performance, and meet key customer needs to face the biomarker assay development challenges encountered during drug development programs and regulatory studies.

Adding to the Company’s existing range of high-quality ready-to-use kits and solutions, the new kits enable high quality data to be generated through well characterized kit reagents and standards, whilst providing a high sensitivity and wide dynamic range to cover the full spectrum of cytokine levels seen in disease states or pharmacodynamic studies. The Gyrolab Biomarker Kits offer convenience and an expedited analytical solution for biomarker quantification by removing the need for assay development. High throughput and automated analyses reduce manual intervention, enable short turnaround times and accelerate data-driven decisions.

As the use of biomarkers in biotherapeutic development continues to increase, single analyte assays with high reproducibility are in high demand. To date, customers have been using the open Gyrolab platform for development of biomarker assays. The introduction of new plug and play kits increase the utility of the platform by removing the timelines needed for assay development and offer a combination of advantages to meet the customer needs in the area.

Mark Vossenaar, General Manager Biopharmaceutical Development Division, Gyros Protein Technologies, commented: “Biomarker assay development is time and resource intensive, requires a high level of expertise, and often comes at a high cost. This is why commercial immunoassay kits are growing in popularity. The introduction of the five new Gyrolab Human Cytokine Kit Reagents as first in a growing range of biomarker kits represents our commitment to building on the Company’s proven expertise to implement innovative technologies that enable scientists to quickly generate high quality biomarker data utilized for critical decision making for drug safety and efficacy.”

Media Contact:

Dr Ben Rutter

Zyme Communications

Email: [email protected]

Mark Vossenaar

Gyros Protein Technologies

Email: [email protected]

About Gyros Protein Technologies https://www.gyrosproteintechnologies.com/

Gyros Protein Technologies enables bioanalytical solutions and peptide synthesis, helping scientists increase biomolecule performance and productivity in research, drug discovery, pre-clinical and clinical development, and bioprocess applications. Proprietary high performance nanoliter-scale immunoassay platforms, Gyrolab^® xPand, and Gyrolab xPlore™, and Gyrolab immunoassay kits are used by scientists at leading pharmaceutical, biotech, CRO, and CMO companies in the development and manufacturing of various biotherapies including those based on peptides, antibodies, cell and gene therapies and vaccines. Gyrolab immunoassays provide key workflow advantages of speed, automation, and low reagent usage, and assay quality advantages of wide dynamic range with robust precision and reproducibility in applications including pharmacokinetics/pharmacodynamics, immunogenicity, and analysis of bioprocess-related impurities. Our low to mid-scale peptide synthesizer platforms, PurePep^® Chorus, Symphony^® X, and PurePep^® Sonata+, and chemistries deliver uncompromising purity, flexibility, and quality synthesis for discovery and pre-clinical studies of simple to complex multifunctional peptides. Our peptide synthesis and bioanalytical solutions accelerate the discovery, development, and manufacturing of safer biotherapeutics. Gyros Protein Technologies is part of the Biopharmaceutical Development Division of Mesa Laboratories, Inc. (Nasdaq: MLAB).

Forward Looking Statements

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