Life Technologies Signs Collaborative Agreement with Douglas Scientific

CARLSBAD, Calif., and ALEXANDRIA, Minn.,– Life Technologies Corporation and Douglas Scientific LLC today announced they have signed a collaboration and co-marketing agreement to optimize technologies from both companies and provide seamless

solutions designed for high-throughput genotyping applications. This collaboration will leverage Life’s industry-leading TaqMan® Assays and Douglas’s disruptive Array Tape™ Platform.

The growing demand for genetic marker screening has led to a greater need for high-throughput genotyping technology that can provide answers for researchers faster and more accurately with affordable, scalable solutions. While other systems enable genotyping of hundreds of samples, combining the TaqMan® SNP Genotyping Assays and Array Tape™ Platform allows customers to easily generate hundreds of thousands of data points per day.

“Taqman® is one of the most widely used assays for SNP genotyping. Optimizing the Array Tape™ Platform for this chemistry was a natural fit for our markets and applications,” says Dan Malmstrom, President and COO at Douglas Scientific. “With preset protocols and optimized instrumentation our customers will realize their throughput and economic goals while

experiencing improvements in efficiency and data quality.”

The level of throughput and accuracy reached by combining these technologies is of particular benefit to the plant agricultural biotechnology and animal breeding industries for marker-assisted selection experiments. Genetic selection methods are now essential to enable these industries to keep pace with the food demands of the growing global population. Other animal, human and drug discovery research applications that require industrial-scale genotyping will also benefit

from this powerful combination.

“The high throughput capacity of the Array Tape™ system is highly complementary to our realtime PCR portfolio, and in particular, our TaqMan® Assays,” said Chris Linthwaite, Head of Genetic Analysis at Life Technologies. “Customers around the world can now leverage a complete solution for high-throughput genotyping – from sample prep to TaqMan® Assays and

the Array Tape™ system, which together offer the industry’s highest quality solution at the affordable cost and high throughput they need.”

Array Tape™ is a continuous polypropylene strip, serially embossed with reaction wells in customized volumes and formats. With miniaturized reaction wells, this thin (0.3 mm) and flexible solution allows 200 microplate equivalents (76,800 reaction wells) to be spooled onto a single, compact reel. It’s an automated, adaptable microplate replacement for high-throughput screening. Douglas Scientific provides inline, modular instrumentation that is fully integrated

and optimized for use with Array Tape™ including: Nexar® liquid handling and assay processing system, Soellex® thermal cycler, Araya® fluorescent detection instrumentation and software solutions. The platform enables a continuous reel-to-reel process flow to maximize throughput and reduce costs.

Life Technologies offers Custom TaqMan® SNP Genotyping Assays for any species of interest. The TaqMan® portfolio also includes 4.5 million pre-designed TaqMan® SNP Genotyping Assays ideally suited for biomarker screening applications and confirmatory studies following next-generation sequencing experiments. They are designed to accurately detect and quantify

genetic variations in DNA samples associated with particular phenotypes of interest. The TaqMan® portfolio also includes market-leading TaqMan® Master Mix reagents and sample preparation kits such as the TaqMan® Sample-to-SNP kit. They are part of a comprehensive portfolio of products and technologies to empower human, plant and animal sciences research.

About Life Technologies

Life Technologies Corporation (NASDAQ: LIFE) is a global biotechnology company with customers in more than 160 countries using its innovative solutions to solve some of today’s most difficult scientific challenges. Quality and innovation are accessible to every lab with its reliable and easy-to-use solutions spanning the biological spectrum with more than 50,000

products for agricultural biotechnology, translational research, molecular medicine and diagnostics, stem cell-based therapies, forensics, food safety and animal health. Its systems, reagents and consumables represent some of the most cited brands in scientific research including: Ion Torrent™, Applied Biosystems®, Invitrogen™, GIBCO®, Ambion®, Molecular

Probes®, Novex®, and TaqMan®. Life Technologies employs approximately 10,400 people and upholds its ongoing commitment to innovation with more than 4,000 patents and exclusive licenses. LIFE had sales of $3.7 billion in 2011. Visit us at our website: https://www.lifetechnologies.com.

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