NANOLIVE LAUNCHES THE SMART MITOCHONDRIAL ASSAYLIVE: A BREAKTHROUGH FOR BIOPHARMA, COSMETICS AND ACADEMIA

Tolochenaz, Switzerland — Nanolive SA proudly announces its latest innovation, the Smart Mitochondrial Assay^LIVE, the first label-free tool for real-time mitochondrial analysis.

This AI-powered assay provides unprecedented accuracy in studying mitochondrial dynamics while preserving cell viability, setting a new standard for drug discovery, toxicology, and disease research.

Figure 1: Nanolive’s holotomographic imaging and mitochondrial detection. Nanolive’s holotomographic technology creates high resolu-tion, label-free images of cells and their organelles. Contrast is generated by the intrinsic refractive index properties of cellular structures (left). Refractive index image plus multi-colored digital segmentation of mitochondria, powered by the Smart Mitochondrial Assay ^LIVE (right).

KEY BENEFITS:

Real-time, label-free imaging eliminates staining artifacts and phototoxicity.
AI-driven quantification automates mitochondrial morphology and network analysis.
Unbiased, reproducible results enhance drug development and toxicology studies.
Cost-efficient, streamlined workflows save time and reduce experimental variability.
Predictive insights improve understanding of cell health and treatment response.

TRANSFORMING MITOCHONDRIAL RESEARCH IN BIOPHARMA, COSMETICS AND ACADEMIA

The Smart Mitochondrial Assay^LIVE is designed for a wide range of applications, including:

Drug discovery & development – Assess compound efficacy and toxicity by monitoring and quantifying mitochondrial responses in live cells.
Cancer metabolism studies – Understand the role of mitochondrial dynamics in tumor progression and therapeutic resistance.Aging & longevity research – Monitor mitochondrial health over time to explore cellular aging mecha-nisms.
Toxicology & safety screening – Improve preclinical testing by detecting early mitochondrial stress and damage.Stefan Milde, Imaging Lead at bit.bio, tested the Smart Mitochondrial Assay^LIVE and highlights its impact: “The introduction of the label-free Smart Mitochondrial Assay^LIVE is a very exciting development, delivering a range of metrics that allow us to interrogate the dynamics of mitochondrial biology in undisturbed, live cells in unprece-dented detail. This new module will be an invaluable tool for the deep phenotyping of our opti-ox powered human iPSC-derived cells and disease models.”
An optional fluorescence module adds multimodal capabilities for visualizing fluorescent drugs, nanoparticles, and molecular targets alongside mitochondrial behavior.

Nanolive’s Smart Mitochondrial Assay^LIVE is transforming mitochondrial research, empowering scientists with faster, more reliable insights for biopharma, cosmetics, and longevity studies. Learn more at www.nanolive.com.

ABOUT NANOLIVE SA

Nanolive SA is a Swiss-based company pioneering label-free live cell imaging and AI-driven digital analysis. By combining cutting-edge artificial intelligence with high-content, high-resolution, non-invasive imaging, Nanol-ive extract unparalleled quantitative data at the single-cell and organelle level—empowering scientists with richer, actionable insights to advance drug discovery, cosmetics development, and academic research.

NANOLIVE LAUNCHES THE SMART MITOCHONDRIAL ASSAYLIVE: A BREAKTHROUGH FOR BIOPHARMA, COSMETICS AND ACADEMIA

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