Charge Variant Kit revolutionizes antibody development with time savings and efficiency

WEST LAFAYETTE, Ind. – Novilytic, an innovator in molecular recognition technology, is excited to announce the release of its Proteometer-CV Kit. This new consumables kit offers groundbreaking advancements in charge variant (CV) analysis. It is specifically designed for scientists focused on developing monoclonal antibodies (mAbs), bispecific antibodies, or fusion proteins with a human Fc region.

Unlike traditional CV methods that demand extensive sample preparation, purification, and sophisticated instrumentation, the Proteometer-CV allows for rapid analysis directly from clarified fermentation broth in less than 25 minutes without sample preparation. The assay works with a dual pump HPLC equipped with a fluorescence detector. The technology of the Proteometer-CV assay significantly reduces the reliance on conventional methods that require Protein A purification.

Key Features and Benefits:

No Protein A Purification Required: Streamlines the process, reducing sample handling and associated errors

Low Sample Requirements: Efficient analysis with minimal sample volume required

Rapid Serial Analysis: Facilitates streamlined processing for higher throughput than Pro A-iCEF or Pro A-HPLC

Simplified Workflow: Easy mobile phase preparation with provided components

In-Broth Technology: The only solution performing CV analysis directly in clarified fermentation broth, ensuring sample integrity

Rapid Turnaround: Complete analysis in 25 minutes from sampling to data

Plug-and-Play: Comes with all components needed for analysis with minimal method development

“We are proud to introduce the Proteometer-CV as a breakthrough technology in the field of antibody development,” said Paul Dreier, BSc., MBA, Novilytic CEO. “This kit addresses a critical bottleneck in drug development processes by providing a fast, accurate, cost-effective CV analysis without sample preparation. It represents a significant advancement in our mission to provide technology that empowers scientists to accelerate the development of lifesaving medicines.”

The Proteometer-CV Kit includes all necessary components and easy-to-follow instructions to simplify and expedite the analysis process.

About Novilytic:

Novilytic is a leader in molecular recognition technology. Their Proteometer product line is revolutionizing drug development and clone selection by eliminating sample preparation steps that were previously industry-standard. Their transformational technology fundamentally changes mAb production by providing near-real-time molecular structure analysis. This reduces the time and cost of drug development and ultimately helps bring lifesaving treatments to the market faster. For more information, visit Novilytic.com.