SOUTH EASTON, Mass. — Pressure BioSciences, Inc. (OTCQB: PBIO) (“PBI” and the “Company”), a leader in the development and sale of broadly enabling pressure cycling technology (“PCT”)-based sample preparation solutions to the worldwide life sciences industry, announced it has been added to the Richmond Club Index, which has outperformed the S&P 500 Index by an average of 11% each year since its inception ten years ago. The Richmond Club boasts roughly 550 members, comprised of a mix of investment advisors, fund managers, analysts, and members of the media.

Inclusion in the Richmond Club Index is difficult to achieve. To be invited, the Richmond Club initially screens thousands of publicly-traded companies, chooses a few to interview, then selects the best company among the finalists that it believes is the most undervalued relative to its peers, and also offers excellent growth potential.

Mr. Scott Barber, President of the Richmond Club, commented: “We believe there are two primary reasons for the Richmond Club Index’s success to date: (i) we carefully select only top quality, undervalued, high growth potential companies to add to the Index, and (ii) we have been highly successful in expanding the shareholder base of selected companies by showcasing them to our expanding base of investors, now at nearly 550 members. This added investor exposure tends to increase the liquidity of the selected company’s stock, while putting upward pressure on the price.”

Mr. Richard T. Schumacher, President and CEO of PBI, said: “We are very pleased that Pressure BioSciences has been selected for addition into the Richmond Club Index. It is most impressive that the Index has outperformed the S&P 500 Index over the past ten years while expanding the shareholder base of Index companies. We are particularly delighted by the exposure that PBI will be getting to the Richmond Club’s 500-plus members, comprised of an assortment of investors and investing professionals, many of whom will be hearing the PBI story for the first time. This new investor recognition, building upon PBI’s recent growth momentum together with important financial, strategic marketing, and new product achievements, lead us to believe that 2016 will be our most successful year to date.”

About Pressure BioSciences’ Presentation to the Richmond Club

PBI will present a business overview to the Richmond Club’s members on Wednesday, April 13 and again in approximately six months. PBI’s presentation will take place at the centrally located National Club, which is two blocks from the Toronto Stock Exchange. To get the PBI story out to the roughly 550 Richmond Club members, a video will be taken of Mr. Schumacher and synchronized with the Company’s PowerPoint slides. This will allow investors on the internet to hear and see exactly what is observed by the live audience. A link to the video will be emailed to all members within five days of the presentation. Internet web statistics show that each video is seen 300-500 times over the first thirty days of the video being posted on the Richmond Club website.

About Pressure BioSciences, Inc.

Pressure BioSciences, Inc. (“PBI”) (OTCQB: PBIO) develops, markets, and sells proprietary laboratory instrumentation and associated consumables to the estimated $6 billion life sciences sample preparation market. Our products are based on the unique properties of both constant (i.e., static) and alternating (i.e., pressure cycling technology, or PCT) hydrostatic pressure. PCT is a patented enabling technology platform that uses alternating cycles of hydrostatic pressure between ambient and ultra-high levels to safely and reproducibly control bio-molecular interactions. To date, we have installed nearly 300 PCT systems in approximately 160 sites worldwide. There are over 100 publications citing the advantages of the PCT platform over competitive methods, many from key opinion leaders. Our primary application development and sales efforts are in the biomarker discovery and forensics areas. Customers also use our products in other areas, such as drug discovery & design, bio-therapeutics characterization, soil & plant biology, vaccine development, histology, and forensic applications.

About The Richmond Club and the Richmond Club Index

The Richmond Club is celebrating its 17th year of helping its roughly 550 members to profit from investing in the Club’s Index of top quality, undervalued, high growth potential companies. Richmond Club members are a mix of investment advisors, fund managers, analysts, and members of the media. Companies in the Richmond Club Index are invited to make a presentation every six months (twice over the twelve month term). To cover the costs of the investor luncheon presentations, video production and web promotion, PBI has agreed to pay Streetwise Investors Club, Inc., owner of the Richmond Club, $1,450 U.S. per month for the twelve month term that PBI will be in the Richmond Club Index.