SOUTH EASTON, Mass.,– Pressure BioSciences, Inc. (OTCQB: PBIO) (“PBI”) and LEAP Technologies (“LEAP”), (together “the companies”), today announced the signing of a strategic co-development, co-marketing, and co-selling agreement (the “Agreement”). Under the Agreement, the companies plan to develop a next generation sample preparation system by combining PBI’s patented pressure cycling technology (“PCT”) platform with LEAP’s proprietary robotics and lab automation equipment. The companies share an industry focus in proteomics sample preparation, primarily in mass spectrometry. PBI and LEAP believe that by combining the best attributes of both technology platforms, they can develop a sample preparation system superior in quality and robustness to current methods.

Proteomics is the study of the structure and function of proteins. The number of researchers studying proteomics has grown in recent years. Their studies have provided new and important insights into human health, and have resulted in a better understanding of diagnosis, prevention, control, prognosis, and possible cures of various diseases and clinical conditions. High-quality sample preparation is critical to proteomic research studies. To that end, automated sample preparation methods increase the precision and quality of laboratory testing, which in-turn increases the probability of discovery. Increased discovery leads to the development of new and improved vaccines, therapeutics and diagnostics.

Mr. Werner Martin, CEO of LEAP Technologies, said: “PCT is a powerful and enabling technology platform. Because of its clear advantages, mass spectrometry laboratories have begun to integrate PCT into their standard sample preparation workflow, even though the PCT method has not yet been fully automated. This has created a wonderful opportunity for us to partner with Pressure BioSciences, as we have the experience and expertise to bring automation to their patented PCT Platform. Over the past 20 years, we have developed a strong reputation in robotics and laboratory automation while working with many of the leading life sciences companies in the world, such as Waters Corporation and Agilent Technologies. With a growing need for automation, we look forward to developing, marketing, and selling the next generation sample preparation system for proteomics with our colleagues at PBI.”

Mr. Richard T. Schumacher, President and CEO of PBI, remarked: “We are very excited to have this opportunity to partner with a well-established and universally respected robotics and lab automation company like LEAP. We already have a foothold in the mass spectrometry sample preparation area, but the ability to build PCT into an automated workflow using LEAP’s proprietary equipment and software should help us increase our penetration in the mass spectrometry area, and in other areas of the estimated $6 billion life sciences sample preparation market. We believe that this added penetration will result in increased revenue for both PBI and LEAP in 2012, and beyond.”

About LEAP Technologies

LEAP Technologies has been providing proprietary robotics and laboratory automation equipment and support for specific applications for over 20 years. LEAP’s automation solutions allow the research scientist to walk away and run their samples unattended (such as overnight). LEAP has become the automation application “house of choice” to which even the large analytical instrument companies refer their customers. LEAP’s name is synonymous with great support, and with flexible and innovative ideas. With today’s digital communication and fast proliferation of new analytical techniques, LEAP successfully offers its value-added products and services worldwide (world wide support network) through a carefully selected network of smaller companies that share the same spirit.

About Pressure BioSciences, Inc.

Pressure BioSciences, Inc. (“PBI”) (OTCQB: PBIO) is focused on the development, marketing, and sale of proprietary laboratory instrumentation and associated consumables based on Pressure Cycling Technology (“PCT”). PCT is a patented, enabling technology platform with multiple applications in the estimated $6 billion life sciences sample preparation market. PCT uses cycles of hydrostatic pressure between ambient and ultra-high levels to control bio-molecular interactions. PBI currently focuses its efforts on the development and sale of PCT-enhanced sample preparation systems (instruments and consumables) for mass spectrometry, biomarker discovery, bio-therapeutics characterization, vaccine development, soil and plant biology, forensics, histology, and counter-bioterror applications.