S-BIO Launches EZGlyco™ mAb-N Kit with 2-AB for N-Glycan Sample Preparation

From IgG in cell culture for HPLC analysis

HUDSON, N.H. — S-BIO1 has launched today EZGlycoTM mAb-N Kit with 2-AB, a breakthrough new product that enables scientists to analyze N-glycans in IgG and Fc-fusion proteins from culture supernatant samples in a rapid, simplified and streamlined single tube operation. The kit is a valuable tool supporting customers in glycoprotein characterization for biotherapeutic development.

Therapeutic monoclonal antibodies (IgG, mAb) are routinely expressed in recombinant expression systems. N-glycosylation is one of the most important post-translational modifications. Monitoring of glycosylation in antibody development and production directly from cell culture media will shorten the time needed to obtain the N-glycan profiling. HPLC-ready glycan preparation can be performed in less than 2 hours, allowing scientists to purify IgG from cell culture supernatant, release and label N-glycans in one complete kit. “The EZGlyco mAb-N Kit with 2-AB streamlined and rapi

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