In collaboration with the University of Bath, today Sirius announces the upcoming release of a new product, Sirius Scissor.

Randy Mrsny, Professor of pharmacy at the University of Bath, and inventor of the system explains: “Our lab at the University of Bath has focused on asking simple questions related to solving problems involving drug delivery. The pharmaceutical industry has struggled with the fact that some, but not all, protein and peptide drugs injected subcutaneously can have low or variable bioavailability. Importantly, no predictive in vitro systems and no in vivo models have been identified to date to help pharmaceutical scientists understand the basis for these outcomes. I was lucky enough to team up with a very talented post-doc, Hanne Kinnunen. Her studies identified principles that provided the basis for development of the Sirius Scissor system, which we feel can be a useful tool for pharmaceutical scientists to follow the physical and chemical status of a protein or peptide drug as it transitions from conditions used to keep it stable on the shelf prior to injection into the conditions of the human body”.

Karl Box, Chief Scientific Officer of Sirius Analytical, adds: “Sirius and the University of Bath have a long history of successful collaborations, so when we decided to expand our product portfolio into the large molecule world, Bath were an obvious development Partner. Professor Mrsny has many years of experience working with biological drugs gained both in Industry and academia: his and Hanne Kikkunen’s robust approach to research has led to our ability to release a system to market in which we have great confidence – indeed initial in vitro-in vivo correlation results have been extremely encouraging. We are extremely proud of the Sirius Scissor platform, and have been delighted by the overwhelmingly positive response from our customers, with the first commercial systems shipping to the first wave of customers in mid-July.”