SwitchGear Genomics Launches Novel Product Line for Assaying miRNA Activity

MENLO PARK, Calif. – SwitchGear Genomics, Inc., a leading provider of products for studying regulatory elements in the human genome, today announced the launch of a unique product line for studying the activity of miRNAs in living cells. The new SwitchGear Synthetic miRNA Target GoClone™ reporters complement the company’s current genome-wide human 3’UTR GoClone reporter collection.

“Our new synthetic miRNA target GoClone reporters bring researchers one step closer to understanding miRNAs, their targets, and their functions.”

.The collection of synthetic miRNA target reporters contain optimized target sequences cloned downstream of the company’s novel RenSP luciferase gene. These vectors can be used to measure the function and abundance of human and viral miRNAs by measuring the knock-down of luciferase signal due to a miRNA interacting with the optimized target sequence. The synthetic reporters can also be used as strong positive controls in miRNA target validation studies or as biosensors to measure relative levels of endogenous miRNAs in a researcher’s particular cell line.

“Based on strong demand from our customers, we are very pleased to launch this exciting product line,” said Shelley Force Aldred, Ph.D., co-founder and President of SwitchGear Genomics,“Our new synthetic miRNA target GoClone reporters bring researchers one step closer to understanding miRNAs, their targets, and their functions.”

SwitchGear now offers over 900 synthetic miRNA target GoClone reporters for miRNAs in addition to their genome-wide collection of 12,000 human 3’UTR GoClone reporters.

About SwitchGear Genomics, Inc.:

SwitchGear Genomics, Inc. is a leading provider of products for studying regulatory elements in the human genome. The company has developed a comprehensive approach to generate new insights into gene regulatory networks and allow researchers to efficiently screen entire pathways in living cells. SwitchGear was founded in March 2005 by Dr. Richard Myers, Dr. Nathan Trinklein and Dr. Shelley Force Aldred from Stanford University. For more information about SwitchGear, please visit the company’s website at https://www.switchgeargenomics.com.

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