Lincoln, NE – ​Teledyne LABS today announced the launch of the CombiFlash® SFC​ at the ACS Fall 2026 National Meeting in Chicago, introducing a purification platform designed to make supercritical fluid chromatography (SFC) more accessible through a familiar flash chromatography workflow. The CombiFlash SFC enables scientists to explore Flash SFC purification using intuitive operation, simplified method development, and the proven workflow that has made flash chromatography a widely adopted purification technique.​

The CombiFlash SFC was developed to address common purification challenges faced by chromatography users, including increasing demands for purification throughput, long solvent evaporation times, solvent costs, waste generation, and sustainability initiatives. By incorporating supercritical fluid technology into a workflow familiar to flash chromatography users, the system helps laboratories explore new separation capabilities while minimizing the learning curve often associated with implementing new purification approaches.

Using carbon dioxide as the primary mobile phase, CombiFlash SFC can reduce organic solvent consumption while significantly reducing solvent evaporation requirements and post-purification processing burden. The result is a faster, more sustainable purification workflow that helps laboratories improve productivity while lowering solvent use and waste generation.

Unlike many advanced purification platforms that require specialized expertise, CombiFlash SFC was specifically developed to make the benefits of SFC more accessible to existing flash chromatography users through an intuitive, flash-style workflow. Familiar operation, proven PeakTrak® software, disposable columns, solid sample loading capabilities, and straightforward fraction collection provides a natural transition for laboratories already experienced with flash chromatography.

“Flash chromatography became widely adopted because it made purification straightforward, accessible, and practical for everyday laboratory use,” said Joshua Lovell, Business Development Manager for Chromatography at Teledyne LABS. “With CombiFlash SFC, we’re applying those same principles to supercritical fluid chromatography, enabling scientists to explore the benefits of SFC through a workflow that is both familiar and easy to implement.”

The system offers scientists an opportunity to evaluate a purification approach that can complement traditional flash chromatography while addressing applications where conventional flash methods may encounter separation challenges. Internal and collaborative evaluations have demonstrated that Flash SFC can successfully resolve compounds that prove difficult to separate using traditional flash techniques while providing alternative selectivity, a broader eluotropic strength range, and opportunities to reduce or eliminate chlorinated solvent use in purification workflows.

In addition to technical performance, CombiFlash SFC supports laboratory sustainability objectives by reducing organic solvent consumption and associated waste generation while helping improve laboratory efficiency through reduced evaporation and post-purification processing requirements. These benefits can help organizations achieve both productivity and environmental goals without sacrificing purification performance.

Teledyne LABS views CombiFlash SFC as more than a new instrument platform. The technology expands access to Flash SFC purification by combining key elements of traditional flash chromatography and supercritical fluid chromatography, providing scientists with an additional tool to address increasingly complex purification challenges. As laboratories seek faster, greener, and more selective purification options, CombiFlash SFC provides a practical pathway for evaluating and implementing SFC within existing workflows.

Visitors to ACS Fall 2026 can experience the CombiFlash® SFC firsthand at the Teledyne LABS booth through live demonstrations, application discussions, and technical presentations highlighting the capabilities of Flash SFC. Scientists unable to attend ACS will also have the opportunity to see the platform at SFC Europe, October 4-6, in Basel, Switzerland.

About Teledyne LABS

Teledyne LABS provides innovative chromatography, laboratory, and analytical solutions that help scientists improve productivity, accelerate discoveries, and solve complex purification and analytical challenges. Through continuous innovation and close collaboration with customers, Teledyne LABS develops technologies that support research, development, and production laboratories worldwide.

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For additional information, product specifications, pricing, or to request a demonstration of the CombiFlash® SFC, visit the CombiFlash SFC product page: https://www.teledynelabs.com/products/chromatography/flash-chromatography/combiflash-sfc