ATLANTA — Thermo Fisher Scientific Inc., the world leader in serving science, today announced its new Thermo Scientific QMS Everolimus Reagent kit, the newest assay in the group of immunosuppressant drug monitoring products. The QMS® Everolimus Reagent kit, which rounds out the company’s full array of immunosuppressant immunoassays that includes Cyclosporine, Tacrolimus and Mycophenolic Acid, was the first to receive U.S. Food and Drug Administration clearance for monitoring the appropriate blood levels of everolimus, a drug that helps prevent rejection in kidney transplant patients. The company will showcase the products at Thermo Scientific booth #1720 during Clinical Lab Expo at AACC 2011, being held July 26 – July 28, at the Georgia World Congress Center, Atlanta, Georgia.

Thermo Scientific products have a proven track record for supplying high-quality reagents, calibrators and controls since 1989. Thermo Fisher’s homogeneous immunoassay products have been used in many major clinical laboratories and drug testing facilities around the world. The newest, ready-to-use liquid QMS Everolimus assay is used as part of therapeutic drug monitoring, an integral part in organ transplant recipient treatment programs. Based on the Thermo Scientific Quantitative Microsphere Systems (QMS), a homogeneous particle-enhanced turbidimetric technology, the Thermo Scientific QMS Everolimus assay is used on automated clinical chemistry analyzers for quantitative determination of everolimus in human whole blood, the active ingredient in the Novartis immunosuppressant drug – trade name Zortress®.

Strategies for immunosuppressive treatment have focused on preventing T lymphocyte cell activation and/or proliferation. Everolimus acts as a proliferation inhibitor. Thermo Scientific QMS Everolimus Calibrator and Control sets are also available for use with the QMS Everolimus Assay. The calibrator kit contains six different calibrators to complete a full six-point calibration, as part of the test procedure; and the QMS Everolimus Control Set contains three levels.

As manufacturers continue to develop new drugs, monitoring the therapeutic ranges for each drug becomes more important. Transplant physicians working with clinical laboratories, for example, must carefully manage dosages to avoid organ rejection caused by low levels of the immunosuppressant drugs or toxicity issues caused by excessive levels of a drug or a potentially lethal combination. Fortunately, Thermo Fisher is constantly innovating, delivering new assay methods, calibrators and controls that build on its history of product reliability, accuracy, ease-of-use and lot-to-lot consistency. For more information about Thermo Scientific QMS Everolimus, please visit booth #1720 during AACC 2011.

Alternatively please call 1-800-232-3342 or +1 49 (0) 851 88689 0 internationally, or visit www.thermoscientific.com/QC.

For access to all Thermo Fisher Scientific news and product photos related to AACC 2011, please visit the online media room at https://www.thermofisher.com/AACC2011.

Zortress® is a registered trademark of Novartis Pharmaceuticals Corporation.

About Thermo Fisher Scientific

Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science. Our mission is to enable our customers to make the world healthier, cleaner and safer. With revenues of nearly $11 billion, we have approximately 37,000 employees and serve customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as in environmental and process control industries. We create value for our key stakeholders through two premier brands, Thermo Scientific and Fisher Scientific, which offer a unique combination of continuous technology development and the most convenient purchasing options. Our products and services help accelerate the pace of scientific discovery, and solve analytical challenges ranging from complex research to routine testing to field applications. Visit www.thermofisher.com.