Embedded Multivariate Analysis Engine features Umetrics technology for PAT solutions

Malmö, Sweden — Umetrics, a world leader in multivariate data analysis (MVDA) software, announces SIEMENS SIPAT™, featuring embedded Umetrics MVDA for the implementation of Process Analytical Technology (PAT). SIPAT improves process understanding and, by permitting a focus on either specific units or total batch quality, its advanced process control allows continuous process improvement in both manufacturing and development applications, enabling real-time product release.

Umetrics’ SIMCA product family is tightly integrated and connected into the SIPAT environment, from model building and management of MVDA models through to the real-time application of these models. The use of MVDA models is enabled by the incorporation of SIMCA®-Q, a calculation engine for real-time multivariate predictions of continuous and batch process results. Also, SIMCA-Batch On-Line (SBOL), a server – client MVDA solution, is interfaced with the SIPAT system.

These real-time quality assurance and fault detection solutions provide substantial cost-savings and improved product quality and process economics.

SIMCA®-Q is the calculation engine of the SIMCA-suite of off-line and on-line software. This suite is used in research, development, and manufacturing for a variety of objectives and purposes all with one common goal; value from data. This platform makes the analysis efficient and easily interpretable, further enhanced by Umetrics’ expertise, training and constructive support.

About SIEMENS

Siemens is a leading supplier to industry. In life science SIEMENS offers products and services in a wide range of areas and applications

In addition to a broad and innovative product portfolio, Siemens offers services and competencies from dedicated engineering services to a multidisciplinary optimization approach throughout pharmaceutical manufacturing in order to address the key issues of the industry and improve their business. This covers not only state-of-the-art technology, but also work on strategic, long-term and comprehensive concepts to benefit the customer’s business worldwide.

For more information about SIPAT, please email info.sipat@siemens.com or visit www.siemens.com/sipat.

About Umetrics

Umetrics is a leading-edge software company which supplies data analysis software and training courses in multivariate analysis and design of experiments. Umetrics provide solutions for both off-line and on-line applications to a broad range of companies, particularly for the pharmaceutical, biotech and chemical sectors. Umetrics is a subsidiary of MKS Instruments, Inc. (NASDAQ: MKSI), a worldwide provider of monitoring and control technologies.

For more information, please visit the Umetrics home page at www.umetrics.com.

The following SIMCA-P+ functionalities are patent protected

OPLS/O2PLS®, SWE-9802229-6, USA-6754543

OSC®, SWE-0000563-7, USA-6853923

PLS TREES, Pending

The following are Trademarks of Umetrics

EZinfo™, PLS TREE™, O2PLS-DA™

And the following are Registered Trademarks of Umetrics

VALUE FROM DATA®, OPLS®, O2PLS®, O2-PLS®, OPLS-DA®,

BATCH FINGERPRINT®, SIMCA®