ISNES, Belgium — VolitionRx Limited (NYSE AMERICAN: VNRX) (“Volition”) today announced that it has entered into a Global Sales and Distribution Agreement with Active Motif for a range of Research Use Only (“RUO”) kits, that are based on its proprietary Nucleosomics^® technology.

Founder and Chairman of Active Motif, Joseph M. Fernandez commented “We are continuously looking for innovative products in the field of epigenetics and believe Nucleosomics^® is a breakthrough technology. We are delighted to announce our strategic relationship with Volition and believe their Nucleosomics^® technology will complement our current range of products and should sell well. These RUO kits will provide researchers throughout the world with a new way to explore epigenetic modifications in circulating cell-free nucleosomes across different diseases from clinical samples. We aim to have the first kit available for sale by the end of June this year and are working with Volition to develop a broad range of assays focused on important targets.”

The RUO kits are based on the same Nu.Q™ immunoassay technology as Volition’s cancer screening panels and may be used to investigate a variety of clinical questions beyond Volition’s core focus in cancer biomarkers. The range of the RUO kits will allow researchers to explore patterns of epigenetic modifications in circulating nucleosomes in disease models, pre-clinical testing and clinical trials across a broad spectrum of clinical applications including cancer, inflammatory and infectious diseases and trauma.  The RUO kits will offer a complete profiling solution from cell to serum.

Chief Executive Officer of Volition, Cameron Reynolds, commented, “We are very happy to be working with Active Motif, who are key players in the field of epigenetics kits. This is a fantastic opportunity for Volition and we expect that it will provide an additional revenue stream beyond that from the expected commercialization of our blood-based tests for cancer. If the assays are developed as a companion diagnostic for another company’s therapeutic, this could also potentially result in further future revenue through a licensing or similar arrangement.”

Dr. Mark Eccleston, Volition’s Business Development Director, commented, “Active Motif is an ideal partner for us, given its great team that has already established relationships with our target customers across the world. Not only will the sale of the RUO kits generate revenue, but such sales will also broaden potential applications of our technology and generate further validation of the Nucleosomics^® platform.”

An interview with Cameron Reynolds and Mark Eccleston on this announcement is available to view at https://volitionrx.com/news/video-gallery

About Active Motif

Active Motif is an industry leader in developing and delivering innovative tools to enable epigenetics and gene regulation research for the life science, clinical and pharmaceutical and drug discovery communities. The company has a world leading portfolio of assays, genome wide services and validated antibodies for use in ChIP-Seq. Active Motif operates globally through its corporate headquarters in Carlsbad, California, regional headquarters in Belgium, Japan and China, as well as a worldwide network of sales and support offices. Active Motif applies a multi-disciplinary approach to create new and modify existing technologies to meet the current and future needs of life science researchers. To learn more please visit www.activemotif.com.

About Volition

Volition is a multi-national life sciences company focused on developing simple, easy to use, cost effective blood tests designed to help diagnose a range of cancers.  The tests are based on the technology platform of Nucleosomics^®, which is the practice of identifying and measuring nucleosomes in the bloodstream or other bodily fluid – an indication that disease is present.

As cancer screening programs become more widespread, Volition’s products aim to help to diagnose a range of cancers quickly, simply, accurately and cost effectively.  Early diagnosis has the potential to not only prolong the life of patients, but also to improve their quality of life.  Volition’s research and development activities are currently centered in Belgium, with additional offices in London, Texas and Singapore, as the company focuses on bringing its diagnostic products to market first in Europe, then in the U.S. and ultimately, worldwide.

For more information about Volition, visit Volition’s website https://volitionrx.com/

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