BALTIMORE — Waters Corporation (NYSE:WAT) today introduced two new Xevo® mass spectrometers and expanded the ionKey/MS System at the 62nd conference of the American Society of Mass Spectrometry (ASMS). The Waters® Xevo G2-XS mass spectrometer, a new high performance benchtop quadrupole time-of-flight (QTofTM) mass spectrometer, and the Xevo TQ-S micro, a new and compact benchtop tandem quadrupole mass spectrometer, take benchtop quantitative and qualitative applications to new levels.

Waters also announced the expansion of the ionKey/MS™ System to the SYNAPT® G2-S, SYNAPT G2-Si, Xevo G2-S QTof and the newly-introduced Xevo G2-XS QTof micro mass spectrometer with new UPLC® grade iKeyTM chemistries.

Additionally, Waters unveiled Progenesis® QI for proteomics Version 2.0, the latest advance in proteomics data analysis software, availability of Omics LLC’s PetroOrg Petroleomics Software on the SYNAPT G2-Si for chemical composition characterization of petroleum and the exclusive rights to Prosolia’s DESI (Desorption Electrospray Ionization) technology for clinical research applications for use with Waters’ time-of-flight mass spectrometers.

Xevo G2-XS QTof Mass Spectrometer

Featuring the new XS Collision Cell, the Xevo® G2-XS mass spectrometer stands alone among its peers in offering uncompromised analytical sensitivity and selectivity in a benchtop QTof mass spectrometer. Shipment of Xevo G2-XS QTof to customer laboratories is expected to begin at the end of the second quarter with MassLynx® software and in the fourth quarter under the UNIFI® Scientific Information System.

“The technology embodied in the Xevo G2-XS benefits laboratory analysis in a number of ways. Most importantly, laboratories now have a dependable option for performing qualitative and quantitative experiments for both known and unknown analytes with a benchtop QTof instrument,” said Brian Smith, Vice President – Mass Spectrometry Operations, Waters Division.

The Xevo G2-XS QTof mass spectrometer combines the new XS Collision Cell with the proven, signature technologies of Tof-MRM, StepWaveTM and QuanTofTM to deliver optimum levels of robust sensitivity and selectivity, resulting in the detection of more low-level compounds than ever before.

For targeted quantitative experiments, Tof-MRM mode delivers a 10-fold improvement in signal-to-noise when compared to full scan mode, resulting in limits of detection and quantification that completely redefine expectations for a benchtop high resolution mass spectrometer.

Xevo TQ-S micro Mass Spectrometer

The Waters Xevo TQ-S micro is designed to acquire sensitive, robust and dependable data at accelerated rates of acquisition for numerous analytes at varying concentrations. Waters intends to commence shipments of the Xevo TQ-S micro system in the third quarter.

“From a price to performance standpoint, the Xevo TQ-S micro is hard to beat. When you add it all up, Xevo TQ-S micro is the smallest, high-performance tandem quadrupole mass spectrometer on the market and is a great new choice for scientists working in food, environmental, pesticides, pharmaceutical bioanalysis and peptide screening,” said Gary Harland, Director – MS Product Management, Waters Division.

Featuring new Xtended Dynamic Range™ technology, the Xevo TQ-S micro mass spectrometer offers an impressive six orders of magnitude of linear dynamic range. This is important for quantifying compounds in samples where the concentrations of individual analytes differ greatly. Furthermore, the wider the operational dynamic range, the easier it is to transfer methods between instruments of differing sensitivities.

The Xevo TQ-S micro’s new Xcelerated Ion Transfer™ (XIT) electronics allow the instrument to acquire as many as 500 MRMs/sec without significantly reducing peak intensities, which no other tandem quadrupole instrument currently offers. This performance boost means that labs performing pesticide screening, drug, and peptide analyses can monitor for a wider range of analytes than ever before.

Xevo TQ-S micro exceeds expectations for a mass spectrometer of its compact size, offering significant enhancements in absolute sensitivity and signal-to-noise over entry-level tandem quadrupole instruments.