Personal image-based cell analyzers integrate the basic principles of high-end cellular imagers and flow cytometry systems into compact, lower-cost instruments, which are oftentimes designed for multiparameter cellular analysis. These instruments utilize fluorescence or trypan blue as the primary form of detection, allowing scientists to detect and obtain a wide array of cellular parameters, including cell […]
Raman spectroscopy is a powerful technique for identification of a wide range of chemicals and compounds, but it was not a practical technique in the lab until about the 1980s and 1990s because of technological limitations. Improvements in fiber optics, optical filter technology and other areas, largely driven by the telecom revolution, helped bring lab […]
Most materials expand when they are heated. This expansion is a complicated process that depends on temperature. For example, when ice is heated to the melting point, the volume actually decreases during the phase transition. Even after the ice is melted, water continues to contract until it reaches a minimum volume at about 4°C. Additional […]
Transfection is the process of introducing foreign material, such as DNA fragments, into a host cell. Microinjection and optical transfection, which is also known as laser-assisted photoporation or optoporation, are two specialized mechanical transfection techniques designed to be used with a wide array of cell types. Although similar in concept, microinjection uses a specialized pipette […]
One of the subsegments driving growth in the Raman spectroscopy market is Raman imaging. The speed and chemical information that imaging provides is helping the technique steadily replace conventional Raman microscopy. Scientists are finding Raman imaging an advantageous technique for a wide variety of industries and applications and are still exploring the technique’s potential. There […]
Many different microscopic methods exist. Some have quite different underlying principles and, consequently, provide very different kinds of information. The ability to correlate the data and images from multiple modes on the same sample offers unique benefits for demanding applications. One combination of techniques that has been successful enough to result in the development of […]
PCR has been around for more than 25 years. As bench space becomes more scarce, the demand for more miniaturized PCR systems has grown. Handheld and portable PCR systems, which were introduced to the market in the early 2000s, add a variety of applications not possible with benchtop PCR systems. In vitro diagnostics and point-of-care […]
Fluorescence correlation spectroscopy (FCS) is a relatively new subsegment of the fluorescence spectroscopy market designed for advanced research. FCS can provide very specific physiochemical information that is most useful in biology and related sectors. Technical advancements in recent decades have allowed the technique to be developed as a commercial instrument technique that is still in […]
Sulfur is one of the most highly regulated elements. When a fuel containing sulfur is oxidized, sulfur dioxide is produced and released into the atmosphere. In addition to its direct health effects as a gaseous pollutant, sulfur dioxide in the air can be transformed into sulfuric acid. Even if the sulfur does not reach the […]
Live cell-imaging incubators are designed to perform in vitro cellular imaging experiments imitating in vivo environmental conditions. They typically integrate an inverted microscope into an incubator, for which a variety of parameters, such as temperature, humidity and carbon dioxide/oxygen concentrations, can be controlled. The imaging technology utilized varies and determines each unit’s applications and capabilities. […]
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IBO (Instrument Business Outlook) is a twice-monthly newsletter aimed at providing decision-makers with the latest and most complete information available on the life science and analytical instrument industry, and lab product markets. IBO delivers the latest curated industry news, information and trends, as well as SDi data and analysis to deliver the maximum in industry insight with a minimum time investment for executives and investors.

