Mass spectrometry (MS) enjoyed a very good 2014 as revenues exceeded 7%, a nice improvement from 2013, led by LC/MS systems, both quadrupole and time-of-flight (TOF) MS instruments. On the other hand, demand for portable, in-field and magnetic-sector MS instruments was anemic, growing less than 3%. This year, the total MS market is expected to […]

The chromatography market increased to nearly $8.17 billion in 2014 on 3.9% growth. This segment’s forecast excludes capillary electrophoresis, which has been moved to the life science segment (see page 2). Also, clinical HPLC has been added as a subsegment. Aftermarket and service demand grew 4.5% and 5.1%, respectively, last year, while demand for initial […]

Merck KGaA and Sigma-Aldrich Consolidation continued in the lab-products market, as less than a year after Thermo Fisher Scientific’s purchase of Life Technologies (see IBO 2/15/14), Merck KGaA announced a $17 billion deal to buy Sigma-Aldrich (see IBO 9/30/14). The deal highlights the importance of scale and diversification and transforms Merck/EMD Millipore into a major […]

A More Focused Approach As economic headwinds in China, industrial and selected government markets continued in 2014, several analytical-instrument and lab-product companies took steps to focus on a narrower set of businesses and product lines, in some cases, divesting assets and, in other cases, consolidating their positions. Among the year’s most prominent product-line exits were […]

As new products introduced this year have shown, HPLC systems continue to evolve. Speed, resolution and ease of use remain key criteria for end-users so as to increase productivity. Vendors continually optimize and develop HPLC techniques, such as UHPLC and LCxLC, to meet these demands. Agilent Technologies, Shimadzu and Thermo Fisher Scientific each launched new […]

Countercurrent chromatography (CCC) is a preparative separation technique using two immiscible liquids. One carries the sample, forming the mobile phase, while the other serves as the stationary phase. The three types of CCC are droplet (DCCC), hydrostatic or centrifugal-partition chromatography (CPC), and hydrodynamic. DCCC uses gravity to draw the mobile phase with the sample through […]

Company Announcements In September, ChromaCon entered into a licensing and technical collaboration agreement with LEWA, granting LEWA license rights to its intellectual property for twin-column–bed chromatography. Microsaic Systems signed an OEM agreement with Gilson. Shipments are expected to start in the first quarter of 2015, with volumes increasing to 50 per year. Product Introductions W. […]

Supercritical fluid chromatography (SFC) is used for small-molecule analysis and the separation of chiral compounds, enantiomers and other low-molecular-weight compounds. SFC differs from traditional LC in that its mobile phase is carbon dioxide, which necessitates a completely pressurized flow path. This pressure must be maintained with automated back-pressure regulators, and the units can be bulky […]

Company Announcements Agilent Technologies agreed in June to distribute Cerno Bioscience’s MassWorks calibration and analysis software with all Agilent GC/MSD systems. The technology increases the mass accuracy of Agilent’s single-quadrupole GC/MSD to enable unknown-compound identification. In August, Agilent Technologies and Shimadzu released each other’s GC instrument control for their respective chromatography data systems (CDSs). INFICON’s […]

Company Announcements Repligen agreed to acquire in June the business of Refine Technology, including the Alternating Tangential Flow system, for $24.5 million in cash, stock and contingent milestone payments. The purchase is expected to add $3.5–$4 million in revenue for the remainder of 2014. In June, Repligen appointed Nicolas M. Barthelemy to its Board. Most […]