R&D spending by large pharmaceutical companies is stabilizing despite continued restructuring. However, as pharmaceutical companies continue to streamline R&D, resources are shifting to clinical trials. Forced to balance between cost containment and drug development to secure future revenues, companies are prioritizing investments in drugs with the strongest growth potential, especially for therapies that will both […]
The US government has averted a helium crisis by passing legislation to continue the operation of the Federal Helium Reserve. Responsible for 30% of the world helium supply, the Reserve will transition from government-set pricing to an auction process. Helium is used to operate MRIs and for semiconductor manufacturing, fiber optics, metallurgy and analytical chemistry. […]
For the one thousand public companies that spend the most on R&D, R&D spending increased 5.8% in fiscal 2013 (the fiscal year ending prior to June 30) to $638 billion, down from 9.6% last year. The total share of revenues spent on R&D increased from 3.43% to 3.60%. Computing and electronics, health care, automotive, industrials, […]
Immunotherapy drugs, known as immune checkpoint inhibitors, could revolutionize cancer treatment and become a major drug market. Bristol-Myers Squibb, Merck & Co. and Roche are among the firms developing such drugs, which use the immune system to target tumor cells. Yervoy, made by Bristol-Myers, the market leader, is approved for treating melanoma, but shows potential […]
In the era of productivity pressure, paperless labs and drug development partnerships, standards are becoming a greater issue for laboratory-generated data. Data standardization facilitates the transfer, analysis and storage of data by creating a common language that can be universally read and written. Standards can be applied to many aspects of data, including format and […]
Pressure is growing to require accreditation of US food testing labs. The FDA’s Food Safety Modernization Act could require such accreditation, but a proposal addressing the issue has yet to be released. The US has around 25,000 food testing labs, including 5,000 third-party labs, but less than 5% are accredited. Accreditation organizations and some food […]
In the latest development in the biosimilars market, in September, the European Medicines Agency granted its first approval for a monoclonal antibody biosimilar. IMS Health estimates that biosimilar sales in markets that are highly regulated totaled around $700 million in 2011 and will account for about 2% of the total biotech market by 2016. According […]
The shutdown of the US federal government that began October 1, is having a wide spread impact on science and research. In addition to worker furloughs, researchers cannot access their labs, travel to meetings, or engage in fieldwork. Some extramural researchers report they are also unable to complete fieldwork. Grant processing, reviews and meetings have […]
Researchers are increasingly studying “super responders,” those patients that respond well to a drug that does not work in most people. Academic centers, such as Memorial Sloan-Kettering Cancer Center, MD Anderson Cancer Center and Dana-Farber Cancer Institute, are pursuing such studies in order to find genetic mutations that can be linked to a drug that […]
It has long been held that each person has one genome, meaning each of their cells share the same basic genetic material. Following decades of rare cases that disputed this, the tenet is now being upended by the discovery of a greater number of individuals with multiple genomes. Called chimerism, the condition is being discovered […]
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IBO (Instrument Business Outlook) is a twice-monthly newsletter aimed at providing decision-makers with the latest and most complete information available on the life science and analytical instrument industry, and lab product markets. IBO delivers the latest curated industry news, information and trends, as well as SDi data and analysis to deliver the maximum in industry insight with a minimum time investment for executives and investors.
