NGS technology and utilization have shown rapid progress, including application for clinical diagnostics in areas such as noninvasive prenatal testing (NIPT) and oncology. However, significant challenges remain for the routine use of the technology in diagnostic testing labs. A paper published earlier this year in Applied & Translational Medicine entitled, “Barriers to Clinical Adoption of […]

Company Announcements Human Longevity (HLI) announced in April a 10-year agreement with AstraZeneca to sequence and analyze up to 500,000 DNA samples from clinical samples. The insights will be added to HLI’s Knowledgebase. Takara Bio USA and Integrated DNA Technologies announced a collaboration to support low-input targeted RNA sequencing. TATAA Biocenter agreed to distribute Lexogen’s […]

Company Announcements 10X Genomics announced that the American Arbitration Association denied claims brought against the company and three of its executives by Bio-Rad Laboratories, alleging breach of certain contractual noncompete, nonsoliciation and confidentiality obligations related to Bio-Rad’s purchase of Quantalife (see IBO 10/15/11). HTG Molecular Diagnostics disclosed that as of December 31, 2015, it had […]

Company Announcements In March, Swift Bioscience partnered with TATAA Biocenter, which now distributes its NGS products in Sweden, Denmark, Norway, Germany, Austria, Slovakia and the Czech Republic. In March, 10x Genomics closed a $55 million Series C financing, led by Fidelity Management & Research. Huawei and WuXi AppTec announced a strategic alliance to support the […]

After the primary analysis of NGS data, the power of genomic analysis software lies within its ability to perform secondary and tertiary analysis. During secondary analysis, data reads are reassembled and filtered to represent the underlying biology, while tertiary analysis software analyzes variants and their similarities to references. With advancements in technology and the necessity […]

Currency fluctuations and economic turbulence not only produced a shift among IBO’s 2015 list of the top 30 analytical and life science instrument, aftermarket and lab product companies, but also yielded a calendar year sales decline when translated into US dollars. Total sales for the top 30 companies (see page 6) as reported in US […]

Company Announcements In February, Silicon Biosystems Menarini and Macrogen partnered to develop clinical assays combining their respective digital sorting technology and NGS capabilities. Sophia Genetics and Integrated DNA Technologies announced a strategic partnership, combining their respective DDM advanced analytical platform and xGene target enrichment panels to create NGS solutions for routine clinical diagnostics. Biomedical data […]

Santa Clara, CA 3/7/16—As part of its effort to create an NGS workflow for clinical applications, Agilent Technologies has acquired a 48% stake in Lasergen for $80 million. Lasergen is a developer of nucleotide chemistries, including Lightning Terminators for NGS. Agilent also has an option to acquire the remainder of the company until March 2, […]

Company Announcements SYGNIS announced in December 2015 a US distribution agreement with Lucigen focused on single-cell amplification for NGS in the clinical oncology research market. In January, NRGene signed a comarketing agreement with Illumina to promote its de novo assembly informatics solution exclusively using Illumina technology. PierianDX closed a $9.3 million Series A financing, led […]

The annual Association of Biomolecular Resource Facilities (ABRF) conference was held in Ft. Lauderdale, Florida, this year. Conference attendance increased for the third year in a row and included 559 attendees and 237 exhibitors. ABRF 2017 will be held in San Diego, California. Over three days, the 45 conference presentations and workshops addressed five topic […]