In the February 15 issue, IBO detailed new products introduced at the annual SLAS conference. Our description of NanoTemper Technologies’ Tycho platform was incorrect. The Tycho NT.6 does not utilize MicroScale Thermophoresis, which is used by the company’s Monolith product line. The Tycho is used for assay development and protein characterization to provide a quick check of protein quality in three minutes. However, it is the company’s Monolith system that is used to monitor CRISPR-guide RNA samples, determining rank order and binding affinity.

As Peter Fung, PhD, senior manager, Product Marketing, at NanoTemper told IBO, ”Tycho can be used for both upstream and downstream processing to quickly monitor protein quality. It helps determine which samples to move forward with before committing to other experiments or more detailed characterizations.” He added, “Tycho measures the changes in the intrinsic fluorescence of a protein as a thermal ramp is applied. These changes indicate transitions in the protein’s folded state. This provides information on the integrity and functionality of a sample. Researchers use Tycho to examine the effects of various buffers, different pHs and storage conditions on the quality of their protein samples.”

Regarding the NT.Robotic Autosampler, it is used with the company’s Prometheus NT.Plex to fully automate and screen samples by measuring protein stability.

Our description of StemoniX’s Assay Ready line of pre-plated cells incorrectly identified the number of spheroids per well. Each well contains a single spheroid.

IBO regrets the errors.