In the latest development in the biosimilars market, in September, the European Medicines Agency granted its first approval for a monoclonal antibody biosimilar. IMS Health estimates that biosimilar sales in markets that are highly regulated totaled around $700 million in 2011 and will account for about 2% of the total biotech market by 2016. According […]
The shutdown of the US federal government that began October 1, is having a wide spread impact on science and research. In addition to worker furloughs, researchers cannot access their labs, travel to meetings, or engage in fieldwork. Some extramural researchers report they are also unable to complete fieldwork. Grant processing, reviews and meetings have […]
Researchers are increasingly studying “super responders,” those patients that respond well to a drug that does not work in most people. Academic centers, such as Memorial Sloan-Kettering Cancer Center, MD Anderson Cancer Center and Dana-Farber Cancer Institute, are pursuing such studies in order to find genetic mutations that can be linked to a drug that […]
It has long been held that each person has one genome, meaning each of their cells share the same basic genetic material. Following decades of rare cases that disputed this, the tenet is now being upended by the discovery of a greater number of individuals with multiple genomes. Called chimerism, the condition is being discovered […]
The NIH has released its interim report on the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (see IBO 4/15/13). Prepared by an Advisory Committee to the Director working group, the report is based on consultations with the scientific community and public workshops. It identified six themes: appropriate experimental systems and models; cross boundaries in […]
Wal-Mart has announced that its suppliers will now be required to disclose and ultimately end the use of 10 potentially harmful chemicals found in fragrances, cosmetics, household cleaners and personal care products sold at its stores. The company did not disclose which chemicals the new requirements cover, but stated the chemicals were chosen due to […]
The World Economic Forum’s (WEC) “Global Competitiveness Report 2013–2014” identified Switzerland as the world’s most competitive country. Singapore, Finland, Germany and the US rounded out the top five most competitive countries. To determine rankings, the WEC considered 12 pillars, including innovation, which were based on its annual Executive Opinion Survey, and data from other international […]
Epigenetic modifications are responsible for heritable changes in gene expression that do not affect the gene itself. Chromatin remodeling, DNA methylation and gene expression regulation by non-coding RNAs are all epigenetic mechanisms. Epigenetic mechanisms of action can serve as valuable targets of drug development. In fact, two DNA methylation inhibitors and two histone deacetylase (HDAC) […]
The number of employees at the 11 largest pharmaceutical companies declined 4% to 932,825 between 2007 and 2012. Three firms recorded a decline in headcount: Pfizer (-12%), AstraZeneca (-10%) and Sanofi (-2%). The only company to boost employment by more than 5% was Johnson & Johnson (9%). The annual change last year in employee numbers […]
Conducted this spring, the KPMG “2013 Food and Beverage Outlook Survey” consists of the responses of 100 US senior executives. Most respondents (58%) expect their companies’ capital spending to increase over the next year, but more than a quarter (28%) expect it to stay about the same. During the same period, nearly half (48%) expect […]
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IBO (Instrument Business Outlook) is a twice-monthly newsletter aimed at providing decision-makers with the latest and most complete information available on the life science and analytical instrument industry, and lab product markets. IBO delivers the latest curated industry news, information and trends, as well as SDi data and analysis to deliver the maximum in industry insight with a minimum time investment for executives and investors.
