New Repeat-Free(TM) Probes Available for FISH testing
HUNTINGDON VALLEY, Pa.–Immunicon Corporation (NASDAQ:IMMC – News) announced today the availability of a new product portfolio for Fluorescence In-Situ Hybridization (FISH) testing. The new RF Poseidon™ FISH Probes are available to the life science and diagnostic clinical laboratories.
FISH probes are used to detect gene amplification, gene rearrangements, microdeletions, chromosome duplications and other genetic abnormalities. “By eliminating the repeat sequences in the FISH probes, the RF Poseidon FISH probes allow for a faster hybridization, reduces background and provides more crisp signals than current probes,” stated Leon Terstappen, MD, PhD, Chief Scientific Officer, Immunicon Corporation. “Additionally, we believe the faster assays allow scientists and laboratorians the flexibility to obtain results in about 75% less time than current practices today.”
“The addition of the RF Poseidon FISH probe portfolio to Immunicon’s products expands our molecular diagnostics offering to customers,” said Byron Hewett, President & CEO, Immunicon Corporation. “It allows Immunicon to fully expand into rare cell testing arenas where we believe there are increasing medical needs.”
The RF Poseidon FISH Probes are developed using the proprietary Repeat-Free™ technology developed by Immunicon and the ULS labeling system developed by Kreatech Diagnostics, the Netherlands. The FISH probes are sold by Immunicon Corporation in North America and manufactured and sold by Kreatech Diagnostics in the rest of the world under an agreement entered into by Immunicon and Kreatech in April 2007.
Fluorescence In-Situ Hybridization (FISH)
Fluorescence In-Situ Hybridization is a technique used to look at chromosomes (the parts of the cell that contain genetic information in the form of DNA) or genes (specific regions of DNA in chromosomes that make RNA and proteins). Pieces of DNA containing a fluorescent dye are labeled and added to cells on a glass slide. When viewed under a fluorescent microscope, parts of chromosomes or genes that bind the pieces of DNA show up as colored. FISH is routinely used in an increasing number of molecular diagnostic areas, including disease diagnosis, therapeutic targeting, drug development, gene mapping and karyotyping analysis. FISH specifically is used to detect gene amplification, gene rearrangements, microdeletions, chromosome duplications and viral infections.
About Immunicon Corporation
Immunicon Corporation is developing and commercializing proprietary cell- and molecular-based human diagnostic and life science research products, and is providing certain analytical services to pharmaceutical and biotechnology companies to assist them in developing new therapeutic agents, with an initial focus on cancer disease management. Immunicon has developed platform technologies to identify, count and characterize a small number of rare cells in blood, such as circulating tumor cells and circulating endothelial cells that are important in many diseases and biological processes. Immunicon’s products and underlying technology platforms also have application in the clinical development of cancer drugs and in cancer research and may have applications in other fields of medicine, such as cardiovascular and infectious diseases. For more information, visit www.immunicon.com or www.poseidondiagnostics.com.
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