Orlando, Florida, – Waters Corporation (NYSE: WAT) introduced a new UPLC/MS system at the 57th Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, March 12 – 17. The ACQUITY SQD puts the power of Ultra Performance Liquid Chromatography/Mass Spectrometry (UPLC™/MS) into the hands of chromatographers.

This UPLC/MS system features the new Waters SQ Detector – a benchtop, ultra-compact, single-quadrupole, atmospheric pressure ionization (API) mass detector designed for routine UPLC/MS analyses. With first-of-its-kind IntelliStart™ Diagnostic Software, the ACQUITY SQD tunes and calibrates the mass detector and conducts system performance checks allowing chromatographers to confidently acquire UPLC/MS data in routine analytical and open access applications.

Waters ACQUITY SQD applications include: peak purity/impurity profiling, synthesis confirmation, product deformulation, and enhanced methods development through the use of molecular weight-based peak tracking.

The Waters SQ Detector utilizes rapid scanning speeds of up to 10,000 amu/sec to deliver high quality mass spectral data in a compact package that is 40% smaller than its predecessor, the ZQ™ Mass Detector. The patented ZSpray™ (dual orthogonal sampling) interface – the industry-leading source design for robust LC/MS – includes multi-mode ESCi® ionization switching for atmospheric pressure chemical ionization (APCI) and electrospray (ESI) ionization in the same run, with rapid polarity switching for added productivity. Dedicated IonSABRE™ APCI and atmospheric pressure photo-ionization (APPI) probes are optional. System control and data acquisition are performed within Waters MassLynx™ 4.1 and Empower™ 2 software.

The mass range of the system extends to 2,000 Daltons and is the first complete LC/MS system to feature Waters Connections® INSIGHT™, an intelligent device diagnostic monitoring service that increases system uptime by securely collecting information about instrument conditions and then encrypting and transmitting it to secure proxy servers at Waters. In this way, preventive maintenance procedures can be performed before the scientist is even aware of the need for them.