Digital PCR (dPCR) extends traditional PCR into the realm of real-time quantitative PCR. It is a method used to directly quantify and clonally amplify nucleic acids. It is an accurate and sensitive technique that counts individual nucleic acid molecules for applications such as detection of rare mutations and quantifying viral load, gDNA, cDNA, plasmids or […]
Triple quadrupole LC/MS is one of the most broadly applicable of all MS techniques. One of the markets in which it is widely used is food safety. There are a range of food testing applications for which the technique is amenable, which will help drive solid growth in this market. No single analytical technique is […]
Thermogravimetric analysis (TGA) is one of the most common specific techniques under the broader rubric of thermal analysis. The basic concept of thermogravimetry is relatively simple: over a period of time, the instrument measures the mass of the sample as the temperature is increased. However, many components and software tools enter into the modern TGA. […]
Superficially porous columns (SPCs), which consist of a non-porous core fused with a porous outer layer, has been around for nearly as long as other analytical HPLC column-packing technologies. However, in the past several years, the superficially porous column technology has reinvented itself for the ultra-performance HPLC (UHPLC) era. SPCs are used for smaller particles, […]
Fluorescence spectroscopy is useful for the analysis of a broad range of organic compounds. A subset of fluorescence spectroscopy is lifetime fluorescence, which offers advantages compared with conventional steady-state fluorescence. Although there are less than half a dozen significant competitors in the market, the strong growth forecast for lifetime fluorescence offers potential for new market […]
For certain materials and powders, porosity is a characteristic of great importance. Porosity is a measure of the voids or pores in a solid substance, and is defined as the ratio of the sample’s void volume and total volume. There are a number of ways to measure the void volume, and mercury porosimetry is one […]
Laser capture microdissection (LCM) is a method used to isolate cells from bodies of cells and tissues by utilizing IR and/or UV lasers. LCM was first introduced in 1996 by scientists at the National Institutes of Health and was primarily used to isolate cell groups from fixed tissues. It was not until recently that the […]
Electron probe microanalysis (EPMA) is also known as electron microprobe analysis (EMPA). Among surface scientists, the technique is familiarly known as microprobe or even just “probe.” EPMA falls into the broad category of instruments for surface analysis that uses beams to investigate the surface of sample. In the case of EPMA, an electron beam is […]
A niche but rapidly growing segment of the molecular spectroscopy market is terahertz spectroscopy. It offers a number of advantages over other analytical techniques, and can provide unique molecular information that is complementary to other molecular spectroscopy techniques. There are quite a few vendors that offer or are developing terahertz instrumentation. There is also a […]
Peptide synthesizers work by treating amino acids with reagents to protect functional groups on the molecule where reactions are not desired. Suitably activated amino acids are then added with various reagents. After synthesis, the completed peptide is cleaved from the resin for purification. Peptide synthesizers come in manual, semi-automated and fully automated formats. Manual synthesizers, […]
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IBO (Instrument Business Outlook) is a twice-monthly newsletter aimed at providing decision-makers with the latest and most complete information available on the life science and analytical instrument industry, and lab product markets. IBO delivers the latest curated industry news, information and trends, as well as SDi data and analysis to deliver the maximum in industry insight with a minimum time investment for executives and investors.
