In late 2013, the Tufts Center for the Study of Drug Development studied personalized medicines in the stages beyond Phase II trials. The information used was compiled from commercial databases, public sources and the Center’s own database. Out of 580 identified products, 66 were likely to be marketed as personalized medicines on approval, although a […]

The EPA proposed this month more stringent restrictions on emissions from the 149 petroleum refineries in the US. The new rule would require monitoring of air at refinery fencelines to ensure compliance with standards. Coking units, tanks and flares would be subject to increased emission-control requirements, and the operational requirements of flares would be adjusted […]

According to the latest IBO Business Climate Survey, optimism among executives at analytical instrument and lab product companies and associated suppliers is on the upswing. Seventy-three percent of executives surveyed expect sales for the industry as a whole to increase moderately in the second and third quarters (see graph, page 4). This is a notable […]

The recent and upcoming expiration of patents on several blockbuster drugs and resulting loss of revenue will require pharmaceutical companies to search for new means to grow revenues. Megamergers, which were common in the past, will still occur. However, recent acquisitions by many pharmaceutical firms show a move instead to specialize in specific markets. For […]

Earlier this month, the World Steel Association released its “Short Range Outlook” for apparent steel use (ASU) for 2014 and 2015. In 2013, ASU reached 1,481 megatons, an increase of 3.6%. ASU is forecast to grow 3.1% in 2014 and 3.3% in 2015. In 2013, developing economies’ ASU was almost triple that of developed economies, […]

Spokane, WA 4/30/14—The Spokesman-Review has reported that PerkinElmer will close its Signature Genomics business later this year. Signature provides microarray-based prenatal and other genetics testing services. PerkinElmer told the Spokesman-Review, “Changing market conditions, including a highly unfavorable reimbursement environment, combined with a significant decline in demand for invasive procedures due to the uptake of non-invasive […]

A working group of experts assembled by the US National Human Genome Research Institute has published guidelines for studying how variations in genetic sequence may cause disease in humans. Not all variations play a role in disease, and incorrect assessment of variants can have adverse effects, including incorrect treatments for patients. The guidelines apply to […]

The first of IBO’s biannual new-laboratory roundups focuses on large new academic buildings and facilities for food testing. In addition, the table on page 6 highlights plans for selected new academic translational-research labs, consumer-products labs and pharmaceutical labs. Several US universities are building or have plans for science facilities at least 200,000 ft2 in size. […]

R&D spending, both domestic and abroad, by Pharmaceutical Research and Manufacturers of America (PhRMA) firms in 2013 totaled $51,060 million, up 3.0% compared to a gain of 1.9% in 2012. In 2013, members increased domestic spending 6.9%, a change from 3.1% in 2012, to comprise 79% of total R&D. Spending abroad fell 9.1%, compared to […]