New capabilities include Thermo Xcalibur® software integration and rapid sample injection
Livermore, California — Eksigent Technologies, a leader in the field of microfluidics, today announced that it will debut its upgraded NanoLC-1D Proteomics System at the Association of Biomolecular Resource Facilities Annual Meeting, February 28 – March 2 in Portland, Oregon. The NanoLC System is the first HPLC (High Performance Liquid Chromatography) system to allow nanoscale LC/MS (liquid chromatography-mass spectrometry) without flow splitting, at gradient flow rates of 20-1000 nl/min. The system provides significant enhancements in detection sensitivity and reproducibility for LC/MS proteomics studies, while simultaneously improving ease of system set-up, operation, and maintenance.
The NanoLC system was introduced commercially in 2003 and is already recognized as a leading instrument in the application segment of nanoscale chromatography. The system has been modified with several new features that improve the system’s throughput and ease of use. Dr. Karen Hahnenberger, NanoLC Product Manager, stated, ” Our goal is to provide proteomics researchers with a complete solution to nanoscale LC/MS. Software integration of the NanoLC system with Thermo’s Xcalibur program allows researchers to set up proteomics experiments in one software package, providing integrated control of the LC and mass spectrometer. This complete system integration makes setting up and running proteomics experiments significantly easier.”
The NanoLC system now includes a rapid injection capability to load large samples onto trap or analytical columns. According to Marc Foster, Ph.D., Senior Scientist, “while LC/MS proteomics experiments are run at 100-200 nl/min, the sample size can often be 10 microliters or more. At these low flow rates loading a sample can take hours. With the NanoLC’s new rapid injection feature, large samples can be loaded at a much higher flow rate, usually in a matter of a few minutes instead of hours. Once sample loading is complete, the system promptly resets to the desired analytical flow rate.” A technical note fully describing the rapid injection capability is available on the company’s website, www.eksigent.com.
About Eksigent Technologies
Eksigent Technologies is pioneering microfluidic systems for use in proteomics, drug discovery, medical devices, and other life science applications. Eksigent’s core microfluidic technologies include microscale pumping, microfluidic system design, and microfabrication. Products include the NanoLC system for highly sensitive LC/MS and high throughput HPLC, and the EKPump for precise microscale fluid delivery. More information about the company is available at www.eksigent.com.
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