The 23rd Analytica exhibition and conference took place in Munich, Germany, from April 17 to 20. As usual, it was a roaring success. Although the attendance of 30,000 was down slightly from 32,061 in 2010, it was hard to tell, given the general enthusiasm throughout the exhibition’s five halls. The number of exhibitors was up […]

The life science instrumentation (LSI) market encompasses a broad spectrum of technologies grouped into a dozen categories. LSI technologies range from mature, multibillion dollar markets to high-growth, burgeoning technology segments. Overall, the LSI market is the largest technology sector in the analytical instrument market, accounting for about a quarter of total sales. The LSI market […]

Branford, CT and Tempe, AZ 10/11/11—Roche has agreed to license several technologies developed by Dr. Stuart Lindsay at the Biodesign Institute at Arizona State University and Dr. Colin Nuckolls of Columbia University Nanoscience Center. The technologies include specialized approaches for DNA base sensing and reading and will be used in Roche’s development of a single-molecule, […]

This year marks a new chapter in the second-generation (next-generation or NGS) DNA sequencing market, as a new set of NGS systems hit the market. The first generation of DNA sequencers consisted of capillary electrophoresis (CE) systems employing Sanger sequencing. Third-generation, or single-molecule, systems directly sequence DNA molecules. NGS sequencing technology, which is characterized by […]

Waltham, MA 5/5/11—PerkinElmer has acquired Geospiza, a developer of software systems for the management of genetic analysis and laboratory workflows delivered through a cloud-computing environment. Financial details were not disclosed. PerkinElmer stated that the acquisition supports its Next Generation DNA Sequencing and Analysis Services offerings (see IBO 2/15/11). “The acquisition of Geospiza, along with existing […]

The excitement about and focus on genomic sequencing stems from the high sales growth and untapped potential of massively parallel sequencing technologies, or next-generation sequencing (NGS). The current generation of sequencers employs similar chemistries, yet utilizes unique strategies. Roche’s Genome Sequencer FLX and GS Junior systems use a combination of emulsion PCR, and sequence by […]

Branford, CT 11/01/10—Roche’s 454 Life Sciences has exclusively partnered with DNA Electronics to develop a low-cost, high-throughput DNA sequencing system, which will allow a transition from optical detection to inexpensive, highly scalable electrochemical detection, according to Roche. “We’re pleased to work together with DNA Electronics, the inventors of ISFET [ion sensitive field effect transistor] DNA […]

Carlsbad, CA and Guilford, CT 8/17/10—Life Technologies has agreed to buy Ion Torrent for $375 million in cash and stock. Ion Torrent’s PostLight sequencing technology translates chemical signals into digital information on a semiconductor chip. An additional consideration of $350 million cash and stock will be available upon the achievement of certain technical and time-based […]

Despite the ill effects of the downturn in global economies, the life science instrumentation market has remained relatively stable. The market accounted for the largest share of the analytical instrumentation market, which was nearly $10.3 billion in revenues in 2009. Sales are expected to increase 5.9% in 2010, with demand driven by government-funded research initiatives […]

Edman degradation is a process for protein sequencing first discovered by the Swedish biochemist Pehr Victor Edman in 1950. The technique is characterized by cycles. In a full cycle, the N-terminus of a given peptide is labeled with the reagent phenylisothiocyanate, forming a cyclic compound. Under acidic conditions, the labeled amino acid is cleaved from […]